Heptanedicarboxylic acid en es it fr

Heptanedicarboxylic acid Brand names, Heptanedicarboxylic acid Analogs

Heptanedicarboxylic acid Brand Names Mixture

  • No information avaliable

Heptanedicarboxylic acid Chemical_Formula

C9H16O4

Heptanedicarboxylic acid RX_link

http://www.rxlist.com/cgi/generic3/azelex.htm

Heptanedicarboxylic acid fda sheet

Heptanedicarboxylic_acid FDA

Heptanedicarboxylic acid msds (material safety sheet)

Heptanedicarboxylic_acid MSDS

Heptanedicarboxylic acid Synthesis Reference

No information avaliable

Heptanedicarboxylic acid Molecular Weight

188.221 g/mol

Heptanedicarboxylic acid Melting Point

106.5 oC

Heptanedicarboxylic acid H2O Solubility

2400 mg/L (20°C)

Heptanedicarboxylic acid State

Solid

Heptanedicarboxylic acid LogP

1.646

Heptanedicarboxylic acid Dosage Forms

Cream (20%)

Heptanedicarboxylic acid Indication

For the topical treatment of mild-to-moderate inflammatory acne vulgaris.

Heptanedicarboxylic acid Pharmacology

Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.

Heptanedicarboxylic acid Absorption

Approximately 4% of the topically applied azelaic acid is systemically absorbed.

Heptanedicarboxylic acid side effects and Toxicity

Oral, rat: LD50 = >5 gm/kg.

Heptanedicarboxylic acid Patient Information

Heptanedicarboxylic acid Organisms Affected

Various aerobic and anaerobic microorganisms