Alimix

Category

Alimix




Useful info

Alimix Brand names, Alimix Analogs

Alimix Brand Names Mixture

  • No information avaliable
  • Alimix Chemical_Formula

    C23H29ClFN3O4

    Alimix RX_link

    http://www.rxlist.com/cgi/generic/cisap.htm

    Alimix fda sheet

    Alimix msds (material safety sheet)

    Alimix MSDS

    Alimix Synthesis Reference

    No information avaliable

    Alimix Molecular Weight

    465.945 g/mol

    Alimix Melting Point

    110 oC

    Alimix H2O Solubility

    2.71 mg/L

    Alimix State

    Solid

    Alimix LogP

    3.802

    Alimix Dosage Forms

    Suspension; Tablet

    Alimix Indication

    For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.

    Alimix Pharmacology

    Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.

    Alimix Absorption

    Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.

    Alimix Toxicity

    No information avaliable

    Alimix Patient Information

    No information avaliable

    Alimix Organisms Affected

    Humans and other mammals