Acenalin

Category

Acenalin




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Acenalin Brand names, Acenalin Analogs

Acenalin Brand Names Mixture

  • No information avaliable

    • Acenalin Chemical_Formula

    C23H29ClFN3O4

    Acenalin RX_link

    http://www.rxlist.com/cgi/generic/cisap.htm

    Acenalin fda sheet

    Acenalin msds (material safety sheet)

    Acenalin MSDS

    Acenalin Synthesis Reference

    No information avaliable

    Acenalin Molecular Weight

    465.945 g/mol

    Acenalin Melting Point

    110 oC

    Acenalin H2O Solubility

    2.71 mg/L

    Acenalin State

    Solid

    Acenalin LogP

    3.802

    Acenalin Dosage Forms

    Suspension; Tablet

    Acenalin Indication

    For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.

    Acenalin Pharmacology

    Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.

    Acenalin Absorption

    Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.

    Acenalin Toxicity

    No information avaliable

    Acenalin Patient Information

    No information avaliable

    Acenalin Organisms Affected

    Humans and other mammals