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Risamal Brand names, Risamal Analogs

Risamal Brand Names Mixture

  • No information avaliable

Risamal Chemical_Formula

C23H29ClFN3O4

Risamal RX_link

http://www.rxlist.com/cgi/generic/cisap.htm

Risamal fda sheet

Risamal msds (material safety sheet)

Risamal MSDS

Risamal Synthesis Reference

No information avaliable

Risamal Molecular Weight

465.945 g/mol

Risamal Melting Point

110 oC

Risamal H2O Solubility

2.71 mg/L

Risamal State

Solid

Risamal LogP

3.802

Risamal Dosage Forms

Suspension; Tablet

Risamal Indication

For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.

Risamal Pharmacology

Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.

Risamal Absorption

Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.

Risamal side effects and Toxicity

No information avaliable

Risamal Patient Information

No information avaliable

Risamal Organisms Affected

Humans and other mammals