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Asmanex Twisthaler en es it fr

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Asmanex Twisthaler Marchi, Asmanex Twisthaler Analoghi

Asmanex Twisthaler Marchi miscela

  • Combisor (Mometasone + Salicyclic Acid)

    • Asmanex Twisthaler Formula chimica

    C22H28Cl2O4

    Asmanex Twisthaler RX link

    http://www.rxlist.com/cgi/generic2/momet1.htm

    Asmanex Twisthaler FDA foglio

    Asmanex_Twisthaler FDA

    Asmanex Twisthaler DMS (foglio di materiale di sicurezza)

    Asmanex Twisthaler Sintesi di riferimento

    EL Shapiro, americano Pat. 4,472,393 (1984)

    Asmanex Twisthaler Peso molecolare

    427.361 g/mol

    Asmanex Twisthaler Temperatura di fusione

    218-220oC

    Asmanex Twisthaler H2O Solubilita

    Praticamente insolubile.

    Asmanex Twisthaler Stato

    Solid

    Asmanex Twisthaler LogP

    3.052

    Asmanex Twisthaler Forme di dosaggio

    Spray nasale; Polvere per inalazione; Crema

    Asmanex Twisthaler Indicazione

    L'inalatore è indicato per il trattamento di mantenimento dell'asma come terapia profilattica. Lo spray nasale è indicato per il trattamento dei sintomi nasali della rinite allergica stagionale e perenne allergica.

    Asmanex Twisthaler Farmacologia

    Mometasone è una media potenza sintetico corticosteroide con antinfiammatori, antiprurito e proprietà vasocostrittrice. Gli studi nei pazienti asmatici hanno dimostrato che mometasone fornisce una rapporto favorevole di attualità per l'attività sistemica per il suo effetto primario locale insieme al metabolismo epatico e la mancanza di metaboliti attivi. Anche se efficace per il trattamento di asma, glucocorticoidi non influenzano i sintomi di asma immediatamente. Massimo miglioramento dei sintomi dopo somministrazione per via inalatoria di mometasone furoato non può essere raggiunta da 1 a 2 o più settimane dopo l'inizio trattamento. Quando glucocorticoidi sono interrotto, la stabilità asma può persistere per diversi giorni o più. Mometasone è stato dimostrato in vitro mostrano una affinità di legame per i glucocorticoidi umano recettore che è circa 12 volte quello del desametasone, 7 volte quella di triamcinolone acetonide, 5 volte quella della budesonide, e 1,5 volte quella del fluticasone. Il significato clinico di questi scoperte è ignota.

    Asmanex Twisthaler Assorbimento

    Spray nasale è virtualmente non rilevabile nel plasma

    Asmanex Twisthaler Tossicita

    Il potenziale di effetti tossici acuti in seguito a sovradosaggio con l'inalatore mometasone è basso. Tuttavia, l'abuso abituale del prodotto può causare sintomi di sovraccarico di steroidi, tra cui le irregolarità mestruali, , Acne, obesità, e debolezza muscolare. Singole dosi orali fino a 8000 mg sono state studiate su volontari umani, senza eventi avversi riportati.

    Asmanex Twisthaler Informazioni paziente

    PATIENT'S INSTRUCTIONS FOR USE ASMANEX® TWISTHALER® 220 mcg (mometasone furoate inhalation powder)

    FOR ORAL INHALATION ONLY

    Please read this leaflet carefully before taking ASMANEX® TWISTHALER®. This leaflet does not contain the complete information about this medication. If you have any questions about ASMANEX® TWISTHALER®, ask your healthcare provider or pharmacist.

    IMPORTANT POINTS TO REMEMBER ABOUT ASMANEX® TWISTHALER®

    • Your healthcare provider has prescribed ASMANEX® TWISTHALER®. It contains a medication called mometasone furoate, which is a synthetic corticosteroid. This medication is used as maintenance treatment that helps prevent and control asthma symptoms.

    • ASMANEX® TWISTHALER® is not a bronchodilator. You should not use ASMANEX® TWISTHALER® when you are having sudden symptoms of shortness of breath. Use an inhaled short-acting bronchodilator such as albuterol to relieve sudden symptoms of shortness of breath.

    • Your healthcare provider may prescribe bronchodilators such as albuterol for emergency relief if an acute asthma attack occurs.

    • The inhaler delivers your medication as a very fine powder that you may (b)(4) mell or feel. Whether or not you are able to sense of a dose, not take extra ess your healthcare provider has told you to.

    • Use the inhaler regularly and at the same time each day as prescribed by your healthcare provider. Maximum benefit may not be achieved for 1 to 2 weeks or longer. If your symptoms do not improve in that time frame or if your condition worsens, contact your healthcare provider.

    Do not use the inhaler if you notice that it is not working correctly. Take it to your healthcare provider or pharmacist.

    HOW TO USE

    Remove the ASMANEX® TWISTHALER® from its foil pouch and write the date on the cap label. It's important to throw away the inhaler 45 days after this date or when the dose counter reads "00", whichever comes first.

    Step 1. Open inhaler

    Hold the inhaler straight up with the pink portion (the base) on the bottom. It is important that you remove the cap of the TWISTHALER® while it is in this upright position to make sure that you get the right amount of medicine with each dose.

    Holding the pink base, twist the cap in a counter- clockwise direction to remove it. As you lift off the cap, the dose counter on the base will count down by one. (If you began with the dose counter reading "30," this action will cause it to now read "29.") This action loads the device with the medicine that you are now ready to inhale.

    IT IS IMPORTANT TO NOTE that the indented arrow (located on the white portion of the TWISTHALER®, directly above the pink base) is pointing to the dose counter.

    Step 2. Inhale dose

    Exhale fully. Then bring the TWISTHALER® up to your mouth with the mouthpiece facing toward you. Place it in your mouth, holding it in a horizontal position. Firmly closing your lips around the mouthpiece, take in a fast, deep breath. Since the medication is a very fine powder, you may not be able to feel or taste it after inhalation.

    Remove the TWISTHALER® from your mouth and hold your breath for about 10 seconds, or as long as you comfortably can.

    IMPORTANT: DO NOT BREATHE OUT THROUGH THE INHALER.

    After you take your medicine, it is important that you wipe the mouthpiece dry, if necessary, and immediately replace the cap, firmly closing the TWISTHALER®.

    This is the only way to be sure that your next dose is properly loaded. Be sure that the arrow is in line with the dose-counter window. The cap needs to be put back on and turned in a clockwise direction, as you gently press down. You'll hear a distinctive "click" to let you know that the cap is fully closed.

    IT IS IMPORTANT TO REPEAT STEPS 1 AND 2 EACH TIME YOU INHALE.

    Rinse your mouth after using.

    STORING YOUR INHALER

    Keep your inhaler clean and dry at all times. If the device needs cleaning, gently wipe the mouthpiece with a dry cloth or tissue as needed. Do not wash the inhaler. Avoid contact with any liquids.

    Store in a dry place at 25°C (77F°); excursions permitted to 15-30°C (59-86°F)

    Keep your inhaler out of the reach of young children.

    HOW TO KNOW WHEN YOUR INHALER IS EMPTY

    The inhaler has a dose indicator window on the pink base. It is a dose counter which displays the number of doses remaining. When the unit reads 01, this indicates the last remaining dose. After dose 01, the counter will read 00, and the cap will lock. The unit must then be discarded.

    Asmanex Twisthaler Atto interessato organismi

    Gli esseri umani e altri mammiferi