Categoria
Amodiaquine
Marchi,
Amodiaquine
Analoghi
Amodiaquine
Marchi miscela
Babys Own Cough Syr (Ammonium Chloride + Guaifenesin + Pyrilamine Maleate) Benylin 4 Flu - Syrup (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Benylin Codeine 3.3mg de Syr (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Broncho Tuss Adult (Guaifenesin + L-Ephedrine Hydrochloride + Sodium Camsylate) Broncho Tuss Infant (Guaifenesin + L-Ephedrine Hydrochloride + Sodium Camsylate) Bronchodex Pediatrique (Dextromethorphan Hydrobromide + Guaifenesin + Pheniramine Maleate + Pseudoephedrine Hydrochloride) Calmylin #3 Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Calmylin Codeine D-E Syr (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Calmylin Cough and Flu Liq (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Centracol Pediatrique - Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pheniramine Maleate + Pseudoephedrine Hydrochloride) Cheracol Cough Syrup (Alcohol Anhydrous + Ammonium Chloride + Codeine Phosphate + Guaifenesin) Cold Aid for Birds (Ammonium Chloride + Glycerine + Guaifenesin + Oil of Anise + Sodium Bicarbonate) Cold and Respiratory Aid for Hamsters (Ammonium Chloride + Glycerine + Guaifenesin + Oil of Anise + Sodium Bicarbonate) Cough and Flu Syrup (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syr W.Cod. Pseudoephed.Hcl Guaifenesin (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup Dm Decongestant Expectorant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup Dm Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Cough Syrup Dm-D-E (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup Dm-E (Dextromethorphan Hydrobromide + Guaifenesin) Cough Syrup Dm-Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Cough Syrup W.Guaifenesin W.Dextromethorphan (Dextromethorphan Hydrobromide + Guaifenesin) Creo Grippe Enfants Sup (Camphor + Eucalyptol + Guaifenesin) Creo Grippe Sup Adultes (Camphor + Eucalyptol + Guaifenesin) Dayquil Liquicaps (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Daytime Cold & Flu Liquid Capsules (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Daytime Liquid - Liq (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dimetane Expectorant Liq (Brompheniramine Maleate + Guaifenesin + Phenylephrine Hydrochloride + Phenylpropanolamine Hydrochloride) Dimetane Expectorant-C Syr (Brompheniramine Maleate + Codeine Phosphate + Guaifenesin + Phenylephrine Hydrochloride + Phenylpropanolamine Hydrochloride) Dimetane Expectorant-Dc Syr (Brompheniramine Maleate + Guaifenesin + Hydrocodone Bitartrate + Phenylephrine Hydrochloride + Phenylpropanolamine Hydrochloride) Dm Cough Syrup Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Dm Expectorant Cough Syrup (Dextromethorphan Hydrobromide + Guaifenesin) Dm Plus Decongestant Plus Expector.Ex.St.Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dm Plus Decongestant Plus Expectorant Cough Syrup (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dm Plus Expectorant Syrup (Dextromethorphan Hydrobromide + Guaifenesin) Dm-D-Expectorant Cough and Cold Syrup (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dymetadrine 25 - Tab (Ephedrine Hydrochloride + Guaifenesin) Entex La (Guaifenesin + Phenylpropanolamine Hydrochloride) Entex La Tablets Srt (Guaifenesin + Phenylpropanolamine Hydrochloride) Ephedrine Ii with Guaifenesin (Ephedrine Racemic (Ephedrine Hydrochloride) + Guaifenesin) Ephedrine V with Guaifenesin (Ephedrine Hydrochloride + Guaifenesin) Guaiacol Plus Pwr (Ammonium Chloride + Guaifenesin + Potassium Iodide) I D M Expectorant Tab (Guaifenesin + Potassium Iodide + Pyrilamine Maleate + Theophylline) I.D.M. Solution (Guaifenesin + L-Ephedrine Hydrochloride + Potassium Iodide + Pyrilamine Maleate) Koffex Dm + Decongestant + Expectorant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Koffex Dm + Decongestant + Expectorant Extra Strength (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Koffex Dm + Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Koffex Dm + Expectorant Extra Strength (Dextromethorphan Hydrobromide + Guaifenesin) Koffex Dm-D-E - Liq (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Mielocol Syrup (Aralia Racemosa + Eucalyptol + Guaifenesin + Honey + Poplar Bud + Sanguinaria Canadensis + White Pine + Wild Cherry) Nezger Tab (Acetylsalicylic Acid + Diphenylpyraline Hydrochloride + Guaifenesin + Phenylephrine Hydrochloride) Novahistex Dh Expectorant (Guaifenesin + Hydrocodone Bitartrate + Phenylephrine Hydrochloride) Novahistex Dm Expectorant with Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Novahistex Expectorant with Decongestant (Guaifenesin + Pseudoephedrine Hydrochloride) Novahistine Dm Expectorant with Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Ornade Expectorant Cough Formula (Chlorpheniramine Maleate + Guaifenesin + Phenylpropanolamine Hydrochloride) Pharmitussin Dm (Dextromethorphan Hydrobromide + Guaifenesin) Pulmorex Expectorant Liq (Ammonium Chloride + Diphenhydramine Hydrochloride + Guaifenesin) Pulmosirum Plus Expectorant (Ammonium Chloride + Beechwood Creosote + Cocillana + Eucalyptus Oil + Guaiacol + Guaifenesin + Ipecac + Lobelia Inflata + Menthol + Myroxylon Balsamum + White Pine) Quiex-K1 Syr (Aminophylline + Guaifenesin + Potassium Iodide) Regular Strength Tylenol Cold Chest Congestion (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Robitussin Syrup with Codeine (Codeine Phosphate + Guaifenesin + Pheniramine Maleate) Sudafed Cold and Flu Gel Caps (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Tri-Anamine Expect Antihist Decong Syrup (Guaifenesin + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate) Triaminic Decongest+Expect Liqui-Gels Cap (Guaifenesin + Pseudoephedrine Hydrochloride) Triaminic Dm Daytime Syr (Dextromethorphan Hydrobromide + Guaifenesin + Phenylpropanolamine Hydrochloride) Triaminic Dm Expectorant Syr (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Triaminic Expectorant Dh Syrup (Guaifenesin + Hydrocodone Bitartrate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate) Triaminic Expectorant Syr (Chlorpheniramine Maleate + Guaifenesin + Pseudoephedrine Hydrochloride) Tussin Cough Medicine Dm Antitussive Expectorant Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Vicks Cough Syrup New Improved (Carbetapentane Citrate + Ephedrine + Guaifenesin)
Amodiaquine
Formula chimica
C20H22ClN3O
Amodiaquine
RX link
No information avaliable
Amodiaquine
FDA foglio
Amodiaquine
DMS (foglio di materiale di sicurezza)
Amodiaquine
Sintesi di riferimento
Nessuna informazione disponibile
Amodiaquine
Peso molecolare
355.861 g/mol
Amodiaquine
Temperatura di fusione
208 oC
Amodiaquine
H2O Solubilita
Nessuna informazione disponibile
Amodiaquine
Stato
Solid
Amodiaquine
LogP
4.337
Amodiaquine
Forme di dosaggio
Compresse (orale, 600 mg)
Amodiaquine
Indicazione
Per il trattamento di attacchi acuti di malaria in soggetti non immuni.
Amodiaquine
Farmacologia
Amodiachina, un 4-aminoquinoline simili alla clorochina nella struttura e attività, è stato utilizzato sia come antimalarico ed un agente anti-infiammatorio per più di 40 anni. Amodiachina è almeno altrettanto efficace come la clorochina, ed è efficace contro alcuni ceppi clorochina-resistenti, anche se la resistenza alla amodiachina è stata segnalata. La modalità di azione di amodiachina non è ancora stata determinata. . 4-Aminoquinolines deprimono muscolo cardiaco, mettere in pericolo la conducibilità cardiaca, e di produrre vasodilatazione con conseguente ipotensione. Si deprimono la respirazione e causa diplopia, vertigini e nausea.
Amodiaquine
Assorbimento
Rapidamente assorbito dopo somministrazione orale.
Amodiaquine
Tossicita
LD50 (topo, intraperitoneale) 225 mg / kg, DL50 (topo, orale) 550 mg / kg. Sintomi di sovradosaggio includono mal di testa, sonnolenza, disturbi visivi, vomito, ipokaliemia, collasso cardiovascolare e cardiaco e arresto respiratorio. Ipotensione, se non trattata, può evolvere rapidamente con shock. Elettrocardiogrammi (ECG) può rivelare arresto atriale, ritmo nodale, prolungamento del tempo di conduzione intraventricolare, ampliando del complesso QRS, e bradicardia progressiva che porta alla fibrillazione ventricolare e / o arresto.
Amodiaquine
Informazioni paziente
Amodiaquine
Atto interessato organismi
Plasmodium
