Categoria
Amodiaquine, ring-closed
Marchi,
Amodiaquine, ring-closed
Analoghi
Amodiaquine, ring-closed
Marchi miscela
Babys Own Cough Syr (Ammonium Chloride + Guaifenesin + Pyrilamine Maleate) Benylin 4 Flu - Syrup (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Benylin Codeine 3.3mg de Syr (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Broncho Tuss Adult (Guaifenesin + L-Ephedrine Hydrochloride + Sodium Camsylate) Broncho Tuss Infant (Guaifenesin + L-Ephedrine Hydrochloride + Sodium Camsylate) Bronchodex Pediatrique (Dextromethorphan Hydrobromide + Guaifenesin + Pheniramine Maleate + Pseudoephedrine Hydrochloride) Calmylin #3 Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Calmylin Codeine D-E Syr (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Calmylin Cough and Flu Liq (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Centracol Pediatrique - Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pheniramine Maleate + Pseudoephedrine Hydrochloride) Cheracol Cough Syrup (Alcohol Anhydrous + Ammonium Chloride + Codeine Phosphate + Guaifenesin) Cold Aid for Birds (Ammonium Chloride + Glycerine + Guaifenesin + Oil of Anise + Sodium Bicarbonate) Cold and Respiratory Aid for Hamsters (Ammonium Chloride + Glycerine + Guaifenesin + Oil of Anise + Sodium Bicarbonate) Cough and Flu Syrup (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syr W.Cod. Pseudoephed.Hcl Guaifenesin (Codeine Phosphate + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup Dm Decongestant Expectorant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup Dm Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Cough Syrup Dm-D-E (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Cough Syrup Dm-E (Dextromethorphan Hydrobromide + Guaifenesin) Cough Syrup Dm-Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Cough Syrup W.Guaifenesin W.Dextromethorphan (Dextromethorphan Hydrobromide + Guaifenesin) Creo Grippe Enfants Sup (Camphor + Eucalyptol + Guaifenesin) Creo Grippe Sup Adultes (Camphor + Eucalyptol + Guaifenesin) Dayquil Liquicaps (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Daytime Cold & Flu Liquid Capsules (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Daytime Liquid - Liq (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dimetane Expectorant Liq (Brompheniramine Maleate + Guaifenesin + Phenylephrine Hydrochloride + Phenylpropanolamine Hydrochloride) Dimetane Expectorant-C Syr (Brompheniramine Maleate + Codeine Phosphate + Guaifenesin + Phenylephrine Hydrochloride + Phenylpropanolamine Hydrochloride) Dimetane Expectorant-Dc Syr (Brompheniramine Maleate + Guaifenesin + Hydrocodone Bitartrate + Phenylephrine Hydrochloride + Phenylpropanolamine Hydrochloride) Dm Cough Syrup Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Dm Expectorant Cough Syrup (Dextromethorphan Hydrobromide + Guaifenesin) Dm Plus Decongestant Plus Expector.Ex.St.Syr (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dm Plus Decongestant Plus Expectorant Cough Syrup (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dm Plus Expectorant Syrup (Dextromethorphan Hydrobromide + Guaifenesin) Dm-D-Expectorant Cough and Cold Syrup (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Dymetadrine 25 - Tab (Ephedrine Hydrochloride + Guaifenesin) Entex La (Guaifenesin + Phenylpropanolamine Hydrochloride) Entex La Tablets Srt (Guaifenesin + Phenylpropanolamine Hydrochloride) Ephedrine Ii with Guaifenesin (Ephedrine Racemic (Ephedrine Hydrochloride) + Guaifenesin) Ephedrine V with Guaifenesin (Ephedrine Hydrochloride + Guaifenesin) Guaiacol Plus Pwr (Ammonium Chloride + Guaifenesin + Potassium Iodide) I D M Expectorant Tab (Guaifenesin + Potassium Iodide + Pyrilamine Maleate + Theophylline) I.D.M. Solution (Guaifenesin + L-Ephedrine Hydrochloride + Potassium Iodide + Pyrilamine Maleate) Koffex Dm + Decongestant + Expectorant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Koffex Dm + Decongestant + Expectorant Extra Strength (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Koffex Dm + Expectorant (Dextromethorphan Hydrobromide + Guaifenesin) Koffex Dm + Expectorant Extra Strength (Dextromethorphan Hydrobromide + Guaifenesin) Koffex Dm-D-E - Liq (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Mielocol Syrup (Aralia Racemosa + Eucalyptol + Guaifenesin + Honey + Poplar Bud + Sanguinaria Canadensis + White Pine + Wild Cherry) Nezger Tab (Acetylsalicylic Acid + Diphenylpyraline Hydrochloride + Guaifenesin + Phenylephrine Hydrochloride) Novahistex Dh Expectorant (Guaifenesin + Hydrocodone Bitartrate + Phenylephrine Hydrochloride) Novahistex Dm Expectorant with Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Novahistex Expectorant with Decongestant (Guaifenesin + Pseudoephedrine Hydrochloride) Novahistine Dm Expectorant with Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Ornade Expectorant Cough Formula (Chlorpheniramine Maleate + Guaifenesin + Phenylpropanolamine Hydrochloride) Pharmitussin Dm (Dextromethorphan Hydrobromide + Guaifenesin) Pulmorex Expectorant Liq (Ammonium Chloride + Diphenhydramine Hydrochloride + Guaifenesin) Pulmosirum Plus Expectorant (Ammonium Chloride + Beechwood Creosote + Cocillana + Eucalyptus Oil + Guaiacol + Guaifenesin + Ipecac + Lobelia Inflata + Menthol + Myroxylon Balsamum + White Pine) Quiex-K1 Syr (Aminophylline + Guaifenesin + Potassium Iodide) Regular Strength Tylenol Cold Chest Congestion (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Robitussin Syrup with Codeine (Codeine Phosphate + Guaifenesin + Pheniramine Maleate) Sudafed Cold and Flu Gel Caps (Acetaminophen + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Tri-Anamine Expect Antihist Decong Syrup (Guaifenesin + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate) Triaminic Decongest+Expect Liqui-Gels Cap (Guaifenesin + Pseudoephedrine Hydrochloride) Triaminic Dm Daytime Syr (Dextromethorphan Hydrobromide + Guaifenesin + Phenylpropanolamine Hydrochloride) Triaminic Dm Expectorant Syr (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Triaminic Expectorant Dh Syrup (Guaifenesin + Hydrocodone Bitartrate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate) Triaminic Expectorant Syr (Chlorpheniramine Maleate + Guaifenesin + Pseudoephedrine Hydrochloride) Tussin Cough Medicine Dm Antitussive Expectorant Decongestant (Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Vicks Cough Syrup New Improved (Carbetapentane Citrate + Ephedrine + Guaifenesin)
Amodiaquine, ring-closed
Formula chimica
C20H22ClN3O
Amodiaquine, ring-closed
RX link
No information avaliable
Amodiaquine, ring-closed
FDA foglio
Amodiaquine, ring-closed
DMS (foglio di materiale di sicurezza)
Amodiaquine, ring-closed
Sintesi di riferimento
Nessuna informazione disponibile
Amodiaquine, ring-closed
Peso molecolare
355.861 g/mol
Amodiaquine, ring-closed
Temperatura di fusione
208 oC
Amodiaquine, ring-closed
H2O Solubilita
Nessuna informazione disponibile
Amodiaquine, ring-closed
Stato
Solid
Amodiaquine, ring-closed
LogP
4.337
Amodiaquine, ring-closed
Forme di dosaggio
Compresse (orale, 600 mg)
Amodiaquine, ring-closed
Indicazione
Per il trattamento di attacchi acuti di malaria in soggetti non immuni.
Amodiaquine, ring-closed
Farmacologia
Amodiachina, un 4-aminoquinoline simili alla clorochina nella struttura e attività, è stato utilizzato sia come antimalarico ed un agente anti-infiammatorio per più di 40 anni. Amodiachina è almeno altrettanto efficace come la clorochina, ed è efficace contro alcuni ceppi clorochina-resistenti, anche se la resistenza alla amodiachina è stata segnalata. La modalità di azione di amodiachina non è ancora stata determinata. . 4-Aminoquinolines deprimono muscolo cardiaco, mettere in pericolo la conducibilità cardiaca, e di produrre vasodilatazione con conseguente ipotensione. Si deprimono la respirazione e causa diplopia, vertigini e nausea.
Amodiaquine, ring-closed
Assorbimento
Rapidamente assorbito dopo somministrazione orale.
Amodiaquine, ring-closed
Tossicita
LD50 (topo, intraperitoneale) 225 mg / kg, DL50 (topo, orale) 550 mg / kg. Sintomi di sovradosaggio includono mal di testa, sonnolenza, disturbi visivi, vomito, ipokaliemia, collasso cardiovascolare e cardiaco e arresto respiratorio. Ipotensione, se non trattata, può evolvere rapidamente con shock. Elettrocardiogrammi (ECG) può rivelare arresto atriale, ritmo nodale, prolungamento del tempo di conduzione intraventricolare, ampliando del complesso QRS, e bradicardia progressiva che porta alla fibrillazione ventricolare e / o arresto.
Amodiaquine, ring-closed
Informazioni paziente
Amodiaquine, ring-closed
Atto interessato organismi
Plasmodium
