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  • Metaproterenol Polistirex Formule chimique


    Metaproterenol Polistirex RX lien

    Metaproterenol Polistirex FDA fiche

    Metaproterenol Polistirex msds (fiche de securite des materiaux)

    Metaproterenol_Polistirex MSDS

    Metaproterenol Polistirex Synthese de reference

    O. Thoma, K. Zeile, le brevet américain. 3,341,594 (1967)

    Metaproterenol Polistirex Poids moleculaire

    211.258 g/mol

    Metaproterenol Polistirex Point de fusion


    Metaproterenol Polistirex H2O Solubilite

    9.7mg / L

    Metaproterenol Polistirex Etat


    Metaproterenol Polistirex LogP


    Metaproterenol Polistirex Formes pharmaceutiques


    Metaproterenol Polistirex Indication

    Pour le traitement du bronchospasme, bronchite chronique, l'asthme et l'emphysème.

    Metaproterenol Polistirex Pharmacologie

    Metaproterenol, une amine synthétique, est structurellement et pharmacologiquement analogue à l'isoprotérénol. Metaproterenol est utilisé exclusivement comme un bronchodilatateur. Les effets pharmacologiques des agonistes bêta-adrénergiques médicaments, tels que Metaproterenol, sont au moins en partie attribuable à la stimulation par le biais des récepteurs bêta-adrénergiques adénylcyclase intracellulaire, l'enzyme qui catalyse la conversion de l'adénosine triphosphate (ATP) pour cyclique-3 ', 5'-adénosine monophosphate (AMP-c). Augmentation de c-AMP niveaux sont associées à la relaxation des muscles lisses bronchiques et l'inhibition de la libération de médiateurs de l'immédiate hypersensibilité à partir des cellules, en particulier par les mastocytes.

    Metaproterenol Polistirex Absorption

    3% (biodisponibilité orale de 40%)

    Metaproterenol Polistirex Toxicite

    Les symptômes de surdose comprennent l'angine de poitrine, hypertension ou hypotension, arythmies, nervosité, maux de tête, tremblements, bouche sèche, palpitations, nausées, étourdissements, fatigue, malaise et d'insomnie. DL50 = 42 mg / kg (par voie orale chez le rat).

    Metaproterenol Polistirex Information pour les patients

    Patients Instructions for Use Alupent

    (metaproterenol sulfate USP) Inhalation Aerosol

    1. Insert metal canister into clear end of mouthpiece.

    2. Remove protective cap, invert canister and shake well before each use.

    3. Avoid spraying in eyes.

    4. Enclose mouthpiece with the lips. The base of the canister should be held vertically. The Alupent canister is to be used only with the white Alupent Inhalation Aerosol mouthpiece. This mouthpiece should not be used with other aerosol medications.

    5. Exhale deeply, then inhale slowly through the mouth and at the same time firmly press once on the upended canister base; continue to inhale deeply. Hold your breath for a few seconds and then remove the mouthpiece from the mouth and exhale slowly.

    One inhalation is often enough to obtain relief. The inhalation can be repeated once or twice, if necessary, or as your physician directs. Wait at least two minutes before repeating the inhalation. In most cases, the dose should not be repeated more often than every 3 to 4 hours. No more than 12 inhalations should be taken in one day.

    6. Replace protective cap after use.

    Do not exceed the dose prescribed by your physician. If difficulty in breathing persists, contact your physician immediately.

    Note: When full, the container holds enough medication for at least 200 inhalations: at least 100 inhalations are in the sample unit. Check regularly, by shaking the cylinder or container, to determine whether it contains any medication. When it first seems empty, there are still about ten doses left. Refill containers for the plastic mouthpiece are available when prescribed by your physician.

    Keep the mouthpiece clean. Wash with hot water. If soap is used, rinse thoroughly with plain water.

    Never open the container holding the medication. Opening it is dangerous and renders the contents useless.

    Caution: Contents Under Pressure. Do not puncture or incinerate container. Do not expose to heat or store at temperatures above 120F. Keep out of reach of small children

    Note: The indented statement below is required by the Federal governments Clean Air Act for all products containing or manufactured with chlorofluorocarbons (CFCs): This product contains trichloromonofluoromethane (CFC-11), dichlorodifluoromethane (CFC-12) and dichlorotetrafluoroethane (CFC-114), substances which harm the environment by destroying ozone in the upper atmosphere.

    Your physician has determined that this product is likely to help your personal health. USE THIS PRODUCT AS DIRECTED, UNLESS INSTRUCTED TO DO OTHERWISE BY YOUR PHYSICIAN. If you have any questions about alternatives, consult with your physician

    Metaproterenol Polistirex Organismes affectes

    Les humains et autres mammifères