Levofloxacin
Categorie
Levofloxacin Les marques, Levofloxacin Analogs
Levofloxacin Les marques melange
Levofloxacin Formule chimique
C36H42F2N6O9
Levofloxacin RX lien
http://www.rxlist.com/cgi/generic2/quixin.htm
Levofloxacin FDA fiche
Levofloxacin msds (fiche de securite des materiaux)
Levofloxacin Synthese de reference
Mitscher, Lester A. et al;. J. Med;. 30, 12, 2283-2286 (1987)
Levofloxacin Poids moleculaire
740.751 g/mol
Levofloxacin Point de fusion
No information avaliable
Levofloxacin H2O Solubilite
Insolubles
Levofloxacin Etat
Solid
Levofloxacin LogP
1.268
Levofloxacin Formes pharmaceutiques
Tablet; liquide; Solution
Levofloxacin Indication
Pour le traitement de la conjonctivite bactérienne causée par des souches sensibles des micro-organismes suivants: l'espèce Corynebacterium, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, , Streptococcus (Groupes C / F / G), le groupe viridans streptocoques, Acinetobacter lwoffii, Haemophilus influenzae, Serratia marcescens.
Levofloxacin Pharmacologie
La lévofloxacine, un anti-infectieux des fluoroquinolones, est optiquement actif L-isomère de l'ofloxacine. La lévofloxacine est utilisé pour traiter la conjonctivite bactérienne, sinusite, bronchite chronique, pneumonie d'origine communautaire et la pneumonie provoquée par la pénicilline des souches résistantes de Streptococcus pneumoniae, les infections structure de la peau et la peau, des infections urinaires compliquées et pyélonéphrite aiguë.
Levofloxacin Absorption
L'absorption de l'ofloxacine après doses uniques ou multiples de 200 à 400 mg est prévisible, et la quantité de médicament absorbée augmente proportionnellement avec la dose.
Levofloxacin Toxicite
Les effets secondaires incluent la désorientation, étourdissements, somnolence, bouffées de chaleur et de froid, nausées, troubles d'élocution, de l'enflure et un engourdissement dans le visage
Levofloxacin Information pour les patients
PATIENT INFORMATION
While taking ofloxacin patient should be advised to:
� to drink fluids liberally;
� that mineral supplements, vitamins with iron or minerals, calcium- , aluminum-, or magnesium-based antacids, sucralfate or Videx�, (Didanosine), chewable/buffered tablets or the pediatric powder for oral solution should not be taken within the two-hour period before or within the two-hour period after taking ofloxacin;
� that ofloxacin can be taken without regard to meals;
� that ofloxacin may cause neurologic adverse effects (e. g. , dizziness, lightheadedness) and that patients should know how they react to ofloxacin before they operate an automobile or machinery or engage in activities requiring mental alertness and coordination;
� to discontinue treatment and inform their physician if they experience pain, inflammation, or rupture of a tendon, and to rest and refrain from exercise until the diagnosis of tendinitis or tendon rupture has been confidently excluded;
� that ofloxacin may be associated with hypersensitivity reactions, even following the first dose, to discontinue the drug at the first sign of a skin rash, hives or other skin reactions, a rapid heartbeat, difficulty in swallowing or breathing, any swelling suggesting angioedema (e. g. , swelling of the lips, tongue, face; tightness of the throat, hoarseness), or any other symptom of an allergic reaction
� to avoid excessive sunlight or artificial ultraviolet light while receiving ofloxacin and to discontinue therapy if phototoxicity (e. g. , skin eruption) occurs;
� that if they are diabetic and are being treated with insulin or an oral hypoglycemic drug, to discontinue ofloxacin immediately if a hypoglycemic reaction occurs and consult a physician;
� that convulsions have been reported in patients taking quinolones, including ofloxacin, and to notify their physician before taking this drug if there is a history of this condition.
While taking ofloxacin patient should be advised to:
� to drink fluids liberally;
� that mineral supplements, vitamins with iron or minerals, calcium- , aluminum-, or magnesium-based antacids, sucralfate or Videx�, (Didanosine), chewable/buffered tablets or the pediatric powder for oral solution should not be taken within the two-hour period before or within the two-hour period after taking ofloxacin;
� that ofloxacin can be taken without regard to meals;
� that ofloxacin may cause neurologic adverse effects (e. g. , dizziness, lightheadedness) and that patients should know how they react to ofloxacin before they operate an automobile or machinery or engage in activities requiring mental alertness and coordination;
� to discontinue treatment and inform their physician if they experience pain, inflammation, or rupture of a tendon, and to rest and refrain from exercise until the diagnosis of tendinitis or tendon rupture has been confidently excluded;
� that ofloxacin may be associated with hypersensitivity reactions, even following the first dose, to discontinue the drug at the first sign of a skin rash, hives or other skin reactions, a rapid heartbeat, difficulty in swallowing or breathing, any swelling suggesting angioedema (e. g. , swelling of the lips, tongue, face; tightness of the throat, hoarseness), or any other symptom of an allergic reaction
� to avoid excessive sunlight or artificial ultraviolet light while receiving ofloxacin and to discontinue therapy if phototoxicity (e. g. , skin eruption) occurs;
� that if they are diabetic and are being treated with insulin or an oral hypoglycemic drug, to discontinue ofloxacin immediately if a hypoglycemic reaction occurs and consult a physician;
� that convulsions have been reported in patients taking quinolones, including ofloxacin, and to notify their physician before taking this drug if there is a history of this condition.
Levofloxacin Organismes affectes
Bactéries entériques et d'autres eubactéries
