ID2
Categorie
ID2 Les marques, ID2 Analogs
- 5IUDR
- 5idu
- Allergan 201
- Allergan 211
- Antizona
- Dendrid
- Emanil
- Heratil
- Herpe-Gel
- Herpes-Gel
- Herpesil
- Herpid
- Herpidu
- Herplex
- Herplex Liquifilm
- ID2
- IDU
- IDUR
- IUDR
- Idexur
- Idossuridina [DCIT]
- Idoxene
- Idoxuridin
- Idoxuridina [Inn-Spanish]
- Idoxuridine [Usan:Ban:Inn:Jan]
- Idoxuridinum [Inn-Latin]
- Idu Oculos
- Iducher
- Idulea
- Iduridin
- Iduviran
- Iododeoxyridine
- Iodoxuridine
- Joddeoxiuridin
- Kerecid
- Ophthalmadine
- Spectanefran
- Stoxil
- Synmiol
- Virudox
ID2 Les marques melange
ID2 Formule chimique
C9H11IN2O5
ID2 RX lien
No information avaliable
ID2 FDA fiche
ID2 msds (fiche de securite des materiaux)
ID2 Synthese de reference
Prusoff, et al. Biochim Biophys Acta 32, 295 (1959)
ID2 Poids moleculaire
354.099 g/mol
ID2 Point de fusion
164-166oC
ID2 H2O Solubilite
<0,01 g/100 ml
ID2 Etat
Solid
ID2 LogP
-0.253
ID2 Formes pharmaceutiques
Gouttes ophtalmiques; pommade ophtalmique
ID2 Indication
Pour une utilisation dans la kérato-conjonctivite et de kératite provoquée par le virus herpès simplex.
ID2 Pharmacologie
En idoxuridine structure chimique se rapproche étroitement de la configuration de la thymidine, l'un des quatre blocs de construction de l'ADN (matériel génétique du virus de l'herpès). En conséquence, idoxuridine est capable pour remplacer la thymidine dans l'étape enzymatique de la réplication virale ou la «croissance». La production conséquente de résultats d'ADN défectueux dans une pseudostructure qui ne peuvent pas infecter ou détruire les tissus. En bref, en pré- anticipant une composante vitale dans le matériel génétique du virus de l'herpès simplex, Herplex-D en solution topique détruit la capacité infectieuse et destructive de la matière virale. Le virus a infecté cellulaire ne peut être attaqué pendant la période de synthèse active d'ADN. Cela se produit tôt dans le développement de l'herpès simplex lésion, mais à différents moments dans différentes cellules. Donc, idéalement, , La zone affectée doit rester saturé avec l'agent antiviral.
ID2 Absorption
L'absorption systémique est peu probable administration oculaire suivantes, même lorsque les sécrétions lacrymo-nasal sont avalés, puisque vidarabine est rapidement désaminée dans le tractus gastro-intestinal.
ID2 Toxicite
Une hypersensibilité ou une sensibilité accrue des yeux à la lumière. DL50 = 3080 mg / kg (par voie orale chez la souris).
ID2 Information pour les patients
Description
Idoxuridine (eye-dox-YOOR-i-deen) belongs to the family of medicines called antivirals.
Idoxuridine is used to treat virus infections of the eye.
Idoxuridine is available only with your doctor's prescription, in the following dosage forms:
Ophthalmic
Ophthalmic ointment (U.S. and Canada)
Ophthalmic solution (eye drops) (U.S. and Canada)
Proper Use of This Medicine
For patients using the eye drop form of idoxuridine:
The bottle is only partially full to provide proper drop control.
To use:
First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to
form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the
eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
If you think you did not get the drop of medicine into your eye properly, use another drop.
To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface
(including the eye). Also, keep the container tightly closed.
For patients using the eye ointment form of idoxuridine:
To use:
First, wash your hands. Then pull the lower eyelid away from the eye to form a pouch. Squeeze a
thin strip of ointment into the pouch. A 1-cm (approximately -inch) strip of ointment is usually
enough unless otherwise directed by your doctor. Gently close the eyes and keep them closed for 1
or 2 minutes to allow the medicine to come into contact with the infection.
To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface
(including the eye). After using idoxuridine eye ointment, wipe the tip of the ointment tube with
a clean tissue and keep the tube tightly closed.
Do not use this medicine more often or for a longer time than your doctor ordered. To do so may
cause problems in the eyes. If you have any questions about this, check with your doctor.
To help clear up your infection completely, keep using this medicine for the full time of treatment,
even though your symptoms may have disappeared. Do not miss any doses.
Dosing - The dose of idoxuridine will be different for different patients. Follow your doctor's orders
or the directions on the label. The following information includes only the average doses of idoxuridine.
If your dose is different, do not change it unless your doctor tells you to do so.
The number of doses you use each day, the time allowed between doses, and the length of time you use the
medicine depend on the medical problem for which you are using idoxuridine.
For virus infections of the eye:
For eye ointment dosage form:
Adults and childrenUse every four hours during the day (five times a day).
For eye solution (eye drops) dosage form:
Adults and childrenUse every hour during the day and every two hours during the night. After the eye
condition gets better, use every two hours during the day and every four hours during the night.
Missed dose - If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost
time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Storage - To store this medicine:
Keep out of the reach of children.
Store in the refrigerator or in a cool place because heat will cause this medicine to break down. However,
keep the medicine from freezing. Follow the directions on the label.
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of
the reach of children.
Idoxuridine (eye-dox-YOOR-i-deen) belongs to the family of medicines called antivirals.
Idoxuridine is used to treat virus infections of the eye.
Idoxuridine is available only with your doctor's prescription, in the following dosage forms:
Ophthalmic
Ophthalmic ointment (U.S. and Canada)
Ophthalmic solution (eye drops) (U.S. and Canada)
Proper Use of This Medicine
For patients using the eye drop form of idoxuridine:
The bottle is only partially full to provide proper drop control.
To use:
First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to
form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the
eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
If you think you did not get the drop of medicine into your eye properly, use another drop.
To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface
(including the eye). Also, keep the container tightly closed.
For patients using the eye ointment form of idoxuridine:
To use:
First, wash your hands. Then pull the lower eyelid away from the eye to form a pouch. Squeeze a
thin strip of ointment into the pouch. A 1-cm (approximately -inch) strip of ointment is usually
enough unless otherwise directed by your doctor. Gently close the eyes and keep them closed for 1
or 2 minutes to allow the medicine to come into contact with the infection.
To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface
(including the eye). After using idoxuridine eye ointment, wipe the tip of the ointment tube with
a clean tissue and keep the tube tightly closed.
Do not use this medicine more often or for a longer time than your doctor ordered. To do so may
cause problems in the eyes. If you have any questions about this, check with your doctor.
To help clear up your infection completely, keep using this medicine for the full time of treatment,
even though your symptoms may have disappeared. Do not miss any doses.
Dosing - The dose of idoxuridine will be different for different patients. Follow your doctor's orders
or the directions on the label. The following information includes only the average doses of idoxuridine.
If your dose is different, do not change it unless your doctor tells you to do so.
The number of doses you use each day, the time allowed between doses, and the length of time you use the
medicine depend on the medical problem for which you are using idoxuridine.
For virus infections of the eye:
For eye ointment dosage form:
Adults and childrenUse every four hours during the day (five times a day).
For eye solution (eye drops) dosage form:
Adults and childrenUse every hour during the day and every two hours during the night. After the eye
condition gets better, use every two hours during the day and every four hours during the night.
Missed dose - If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost
time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Storage - To store this medicine:
Keep out of the reach of children.
Store in the refrigerator or in a cool place because heat will cause this medicine to break down. However,
keep the medicine from freezing. Follow the directions on the label.
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of
the reach of children.
ID2 Organismes affectes
Herpes simplex virus
