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Nasonex Nombres de marca, Nasonex Analogos

Nasonex Marca los nombres de mezcla

  • Combisor (Mometasone + Salicyclic Acid)
  • Nasonex Formula quimica

    C22H28Cl2O4

    Nasonex RX enlace

    http://www.rxlist.com/cgi/generic2/momet1.htm

    Nasonex FDA hoja

    Nasonex FDA

    Nasonex MSDS (hoja de seguridad de materiales)

    Nasonex Sintesis de referencia

    EL Shapiro, EE.UU. Pat. 4,472,393 (1984)

    Nasonex Peso molecular

    427.361 g/mol

    Nasonex Punto de fusion

    218-220oC

    Nasonex H2O Solubilidad

    Prácticamente insoluble.

    Nasonex Estado

    Solid

    Nasonex LogP

    3.052

    Nasonex Formas de dosificacion

    Aerosol nasal, por inhalación de polvo, crema

    Nasonex Indicacion

    El inhalador está indicado para el tratamiento de mantenimiento del asma como terapia profiláctica. El spray nasal está indicado para el tratamiento de los síntomas nasales de la rinitis alérgica estacional y perenne alérgica.

    Nasonex Farmacologia

    Mometasona es una síntesis de media potencia con corticosteroides antipruriginoso antiinflamatorio, y las propiedades vasoconstrictoras. Los estudios realizados en pacientes asmáticos han demostrado que proporciona un mometasona relación favorable de los tópicos de la actividad sistémica, debido a su efecto primario local junto con el metabolismo hepático y la falta de metabolitos activos. Si bien es eficaz para el tratamiento del asma, glucocorticoides no afectan a los síntomas de asma inmediatamente. Máxima mejora en los síntomas después de la administración inhalada de furoato de mometasona no se puede alcanzar de 1 a 2 semanas o más después de comenzar el tratamiento. Cuando se suspenden los glucocorticoides, la estabilidad del asma pueden persistir durante varios días o más. Mometasona ha demostrado in vitro que muestran una afinidad de unión para el ser humano con glucocorticoides receptor, que es aproximadamente 12 veces mayor que la de la dexametasona, 7 veces mayor que la de acetato de triamcinolona, 5 veces mayor que la budesonida, y 1.5 veces la de fluticasona. La importancia clínica de estos hallazgos.

    Nasonex Absorcion

    Spray nasal es virtualmente indetectable en plasma

    Nasonex Toxicidad

    El potencial de efectos tóxicos agudos tras una sobredosis con el inhalador de mometasona es baja. Sin embargo, el uso excesivo habitual del producto puede causar síntomas de sobrecarga de esteroides, incluyendo las irregularidades menstruales, , El acné, la obesidad y debilidad muscular. Una sola dosis oral de hasta 8000 mg han sido estudiados en voluntarios humanos sin efectos adversos reportados.

    Nasonex Informacion de Pacientes

    PATIENT'S INSTRUCTIONS FOR USE ASMANEX® TWISTHALER® 220 mcg (mometasone furoate inhalation powder)

    FOR ORAL INHALATION ONLY

    Please read this leaflet carefully before taking ASMANEX® TWISTHALER®. This leaflet does not contain the complete information about this medication. If you have any questions about ASMANEX® TWISTHALER®, ask your healthcare provider or pharmacist.

    IMPORTANT POINTS TO REMEMBER ABOUT ASMANEX® TWISTHALER®

    • Your healthcare provider has prescribed ASMANEX® TWISTHALER®. It contains a medication called mometasone furoate, which is a synthetic corticosteroid. This medication is used as maintenance treatment that helps prevent and control asthma symptoms.

    • ASMANEX® TWISTHALER® is not a bronchodilator. You should not use ASMANEX® TWISTHALER® when you are having sudden symptoms of shortness of breath. Use an inhaled short-acting bronchodilator such as albuterol to relieve sudden symptoms of shortness of breath.

    • Your healthcare provider may prescribe bronchodilators such as albuterol for emergency relief if an acute asthma attack occurs.

    • The inhaler delivers your medication as a very fine powder that you may (b)(4) mell or feel. Whether or not you are able to sense of a dose, not take extra ess your healthcare provider has told you to.

    • Use the inhaler regularly and at the same time each day as prescribed by your healthcare provider. Maximum benefit may not be achieved for 1 to 2 weeks or longer. If your symptoms do not improve in that time frame or if your condition worsens, contact your healthcare provider.

    Do not use the inhaler if you notice that it is not working correctly. Take it to your healthcare provider or pharmacist.

    HOW TO USE

    Remove the ASMANEX® TWISTHALER® from its foil pouch and write the date on the cap label. It's important to throw away the inhaler 45 days after this date or when the dose counter reads "00", whichever comes first.

    Step 1. Open inhaler

    Hold the inhaler straight up with the pink portion (the base) on the bottom. It is important that you remove the cap of the TWISTHALER® while it is in this upright position to make sure that you get the right amount of medicine with each dose.

    Holding the pink base, twist the cap in a counter- clockwise direction to remove it. As you lift off the cap, the dose counter on the base will count down by one. (If you began with the dose counter reading "30," this action will cause it to now read "29.") This action loads the device with the medicine that you are now ready to inhale.

    IT IS IMPORTANT TO NOTE that the indented arrow (located on the white portion of the TWISTHALER®, directly above the pink base) is pointing to the dose counter.

    Step 2. Inhale dose

    Exhale fully. Then bring the TWISTHALER® up to your mouth with the mouthpiece facing toward you. Place it in your mouth, holding it in a horizontal position. Firmly closing your lips around the mouthpiece, take in a fast, deep breath. Since the medication is a very fine powder, you may not be able to feel or taste it after inhalation.

    Remove the TWISTHALER® from your mouth and hold your breath for about 10 seconds, or as long as you comfortably can.

    IMPORTANT: DO NOT BREATHE OUT THROUGH THE INHALER.

    After you take your medicine, it is important that you wipe the mouthpiece dry, if necessary, and immediately replace the cap, firmly closing the TWISTHALER®.

    This is the only way to be sure that your next dose is properly loaded. Be sure that the arrow is in line with the dose-counter window. The cap needs to be put back on and turned in a clockwise direction, as you gently press down. You'll hear a distinctive "click" to let you know that the cap is fully closed.

    IT IS IMPORTANT TO REPEAT STEPS 1 AND 2 EACH TIME YOU INHALE.

    Rinse your mouth after using.

    STORING YOUR INHALER

    Keep your inhaler clean and dry at all times. If the device needs cleaning, gently wipe the mouthpiece with a dry cloth or tissue as needed. Do not wash the inhaler. Avoid contact with any liquids.

    Store in a dry place at 25°C (77F°); excursions permitted to 15-30°C (59-86°F)

    Keep your inhaler out of the reach of young children.

    HOW TO KNOW WHEN YOUR INHALER IS EMPTY

    The inhaler has a dose indicator window on the pink base. It is a dose counter which displays the number of doses remaining. When the unit reads 01, this indicates the last remaining dose. After dose 01, the counter will read 00, and the cap will lock. The unit must then be discarded.

    Nasonex Organismos afectados

    Humanos y otros mamíferos