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Effexin Nombres de marca, Effexin Analogos

Effexin Marca los nombres de mezcla

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  • Effexin Formula quimica

    C18H20FN3O4

    Effexin RX enlace

    http://www.rxlist.com/cgi/generic/oflox.htm

    Effexin FDA hoja

    Effexin FDA

    Effexin MSDS (hoja de seguridad de materiales)

    Effexin MSDS

    Effexin Sintesis de referencia

    I. Hayakava et al., Patente de EE.UU.. 4,382,892 (1983)

    Effexin Peso molecular

    361.368 g/mol

    Effexin Punto de fusion

    250-257 oC

    Effexin H2O Solubilidad

    28,3 mg / ml

    Effexin Estado

    Solid

    Effexin LogP

    1.268

    Effexin Formas de dosificacion

    Solución (inyección IV), Tablet, gotas oftálmicas

    Effexin Indicacion

    Para el tratamiento de las infecciones (tracto respiratorio, riñón, piel, tejidos blandos, infección del tracto urinario), la uretra y la gonorrea cervical.

    Effexin Farmacologia

    Ofloxacino es un antibiótico de quinolona / fluoroquinolonas. Ofloxacina es bactericida y su mecanismo de acción depende de bloqueo de la replicación del ADN bacteriano mediante la unión en sí a una enzima llamada ADN girasa, que permite que el destrenzado necesarios para reproducir una doble hélice de ADN en dos. Cabe destacar que la droga tiene una afinidad 100 veces mayor de la ADN girasa bacteriana que en los mamíferos. Ofloxacino es un amplio espectro antibiótico que es activo frente a bacterias Gram-positivas y Gram-negativas.

    Effexin Absorcion

    La biodisponibilidad de ofloxacina en la formulación del comprimido es de aproximadamente el 98%

    Effexin Toxicidad

    DL50 = 5450 mg / kg (por vía oral en ratones)

    Effexin Informacion de Pacientes

    PATIENT INFORMATION
    Patients should be advised:

    - to drink fluids liberally;

    - that mineral supplements, vitamins with iron or minerals, calcium- , aluminum-, or magnesium-based
    antacids, sucralfate or Videx, (Didanosine), chewable/buffered tablets or the pediatric powder for
    oral solution should not be taken within the two-hour period before or within the two-hour period after
    taking ofloxacin (See Drug Interactions);

    - that ofloxacin can be taken without regard to meals;

    - that ofloxacin may cause neurologic adverse effects (e. g. , dizziness, lightheadedness) and that
    patients should know how they react to ofloxacin before they operate an automobile or machinery or
    engage in activities requiring mental alertness and coordination

    - to discontinue treatment and inform their physician if they experience pain, inflammation, or rupture
    of a tendon, and to rest and refrain from exercise until the diagnosis of tendinitis or tendon rupture
    has been confidently excluded;



    - that ofloxacin may be associated with hypersensitivity reactions, even following the first dose, to
    discontinue the drug at the first sign of a skin rash, hives or other skin reactions, a rapid heartbeat,
    difficulty in swallowing or breathing, any swelling suggesting angioedema (e. g. , swelling of the lips,
    tongue, face; tightness of the throat, hoarseness), or any other symptom of an allergic reaction

    - to avoid excessive sunlight or artificial ultraviolet light while receiving ofloxacin and to discontinue
    therapy if phototoxicity (e. g. , skin eruption) occurs;

    - that if they are diabetic and are being treated with insulin or an oral hypoglycemic drug, to discontinue
    ofloxacin immediately if a hypoglycemic reaction occurs and consult a physician

    - that convulsions have been reported in patients taking quinolones, including ofloxacin, and to notify their
    physician before taking this drug if there is a history of this condition.

    Effexin Organismos afectados

    Bacterias entéricas y otras eubacterias