Zophren
Brand names,
Zophren
Analogs
Zophren
Brand Names Mixture
Zophren
Chemical_Formula
C18H19N3O
Zophren
RX_link
http://www.rxlist.com/cgi/generic/ondansetron.htm
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fda sheet
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msds (material safety sheet)
Zophren
Synthesis Reference
No information avaliable
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Molecular Weight
293.363 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
Solid
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LogP
2.019
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Dosage Forms
Tablet; Liquid
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Indication
For treatment of chemotherapy-induced nausea and vomiting
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Pharmacology
Ondansetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative nausea and vomiting. Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors.
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Absorption
Ondansetron is well absorbed after oral administration and undergoes limited first-pass metabolism.
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side effects and Toxicity
Low blood pressure and fainting, sudden blindness, severe constipation
Zophren
Patient Information
PATIENT INFORMATION
Please follow the link below for more information and the links in Drug_reference region.
http://www.rxlist.com/cgi/generic/ondansetron_wcp.htm
Zophren
Organisms Affected
Humans and other mammals