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Ziprasidone Brand names, Ziprasidone Analogs

Ziprasidone Brand Names Mixture

  • No information avaliable

Ziprasidone Chemical_Formula


Ziprasidone RX_link

Ziprasidone fda sheet

Ziprasidone FDA

Ziprasidone msds (material safety sheet)

Ziprasidone MSDS

Ziprasidone Synthesis Reference

J. A. Lowe III, A. A. Nagel, Eur. pat. Appl. 281,309; eidem, U.S. pat. 4,831,031 (1988, 1989 both to Pfizer).

Ziprasidone Molecular Weight

412.936 g/mol

Ziprasidone Melting Point

>300 oC

Ziprasidone H2O Solubility

No information avaliable

Ziprasidone State


Ziprasidone LogP


Ziprasidone Dosage Forms

Capsule; Injection;

Ziprasidone Indication

For the treatment of schizophrenia

Ziprasidone Pharmacology

Ziprasidone is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Ziprasidone is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Ziprasidone acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Ziprasidone. Ziprasidone's antagonism of muscarinic M1-5 receptors may explain its anticholinergic effects. Ziprasidone's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Ziprasidone's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. Ziprasidone functions as an antagonist at the Dopamine D2 , 5HT-2A , and 5HT-1D receptors, and as an agonist at the 5HT-1A receptor. Ziprasidone also inhibits synaptic reuptake of serotonin and norepinephrine.

Ziprasidone Absorption


Ziprasidone side effects and Toxicity

No information avaliable

Ziprasidone Patient Information

Ziprasidone Organisms Affected

Humans and other mammals