PharmacyCodes



Xatral en es it fr

Xatral Brand names, Xatral Analogs

Xatral Brand Names Mixture

  • No information avaliable

Xatral Chemical_Formula

C19H27N5O4

Xatral RX_link

http://www.rxlist.com/cgi/generic3/uroxatral.htm

Xatral fda sheet

Xatral FDA

Xatral msds (material safety sheet)

Xatral Synthesis Reference

No information avaliable

Xatral Molecular Weight

389.449 g/mol

Xatral Melting Point

No information avaliable

Xatral H2O Solubility

No information avaliable

Xatral State

Solid

Xatral LogP

1.604

Xatral Dosage Forms

Tablet (extended-release)

Xatral Indication

For the treatment of the signs and symptoms of benign prostatic hyperplasia.

Xatral Pharmacology

Alfuzosin is an alpha-adrenergic blocking agent used to treat hypertension and benign prostatic hyperplasia. Accordingly, alfuzosin is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. In the human prostate, alfuzosin antagonizes phenylephrine (alpha1 agonist)-induced contractions, in vitro, and binds with high affinity to the alpha1c adrenoceptor, which is thought to be the predominant functional type in the prostate. Studies in normal human subjects have shown that alfuzosin competitively antagonized the pressor effects of phenylephrine (an alpha1 agonist) and the systolic pressor effect of norepinephrine. The antihypertensive effect of alfuzosin results from a decrease in systemic vascular resistance and the parent compound alfuzosin is primarily responsible for the antihypertensive activity.

Xatral Absorption

Absorption is 50% lower under fasting conditions

Xatral side effects and Toxicity

side effects are dizziness (due to postural hypotension), upper respiratory tract infection, headache, and fatigue.

Xatral Patient Information

PATIENT INFORMATION

Follow the links

http://www.rxlist.com/cgi/generic3/uroxatral_pi.htm

http://www.rxlist.com/cgi/generic3/uroxatral_wcp.htm

http://www.drugs.com/cons/Alfuzosin.html

Xatral Organisms Affected

Humans and other mammals