Wellferon (GlaxoSmithKline)
Brand names,
Wellferon (GlaxoSmithKline)
Analogs
Wellferon (GlaxoSmithKline)
Brand Names Mixture
Wellferon (GlaxoSmithKline)
Chemical_Formula
C860H1353N227O255S9
Wellferon (GlaxoSmithKline)
RX_link
No information avaliable
Wellferon (GlaxoSmithKline)
fda sheet
Wellferon (GlaxoSmithKline)
msds (material safety sheet)
Wellferon (GlaxoSmithKline)
Synthesis Reference
No information avaliable
Wellferon (GlaxoSmithKline)
Molecular Weight
19241.1
Wellferon (GlaxoSmithKline)
Melting Point
Melting point: 61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999)) Davis JM, Narachi MA, Levine HL, Alton NK, Arakawa T. Conformation and stability of two recombinant human interferon-alpha analogs.
Wellferon (GlaxoSmithKline)
H2O Solubility
No information avaliable
Wellferon (GlaxoSmithKline)
State
Liquid
Wellferon (GlaxoSmithKline)
LogP
-0.336
Wellferon (GlaxoSmithKline)
Dosage Forms
Solution (Intramuscular or Subcutaneous Injection)
Wellferon (GlaxoSmithKline)
Indication
For treatment of venereal or genital warts caused by the Human Papiloma Virus
Wellferon (GlaxoSmithKline)
Pharmacology
Upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase) and protein kinase R.
Wellferon (GlaxoSmithKline)
Absorption
No information avaliable
Wellferon (GlaxoSmithKline)
side effects and Toxicity
No information avaliable
Wellferon (GlaxoSmithKline)
Patient Information
No information avaliable
Wellferon (GlaxoSmithKline)
Organisms Affected
No information avaliable