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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C13H17NO
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RX_link
http://www.rxlist.com/cgi/generic3/crotamiton.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
203.28 g/mol
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Melting Point
< 25 oC
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H2O Solubility
No information avaliable
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State
Liquid
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LogP
2.688
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Dosage Forms
Cream
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Indication
For eradication of scabies (Sarcoptes scabiei) and for symptomatic treatment of pruritic skin.
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Pharmacology
Crotamiton is usually used to treat pruritis (itching of the skin) caused by scabies or sunburn. Crotamiton relieves itching by producing what is called a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect. This cooling effect helps to divert your body's attention away from the itching. Due to this cooling effect it is also effective for the relief of sunburn. The drug is also believed to kill scabies through an unknown mechanism.
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Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
DIRECTIONS FOR PATIENTS WITH SCABIES
- Take a routine bath or shower. Thoroughly massage Eurax cream or lotion into the skin from the chin to the toes
including folds and creases.
- Put Eurax cream or lotion under fingernails after trimming the fingernails short, because scabies are very
likely to remain there. A toothbrush can be used to apply the Eurax cream or lotion under the fingernails.
Immediately after use, the toothbrush should be wrapped in paper and thrown away. Use of the same brush in the
mouth could lead to poisoning.
- A second application is advisable 24 hours later.
- This 60 gram tube or bottle is sufficient for two applications.
- Clothing and bed linen should be changed the next day. Contaminated clothing and bed linen may be dry-cleaned,
or washed in the hot cycle of the washing machine.
- A cleansing bath should be taken 48 hours after the last application.
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Organisms Affected
Humans and other mammals