Tysabri (Antegren) Biogen en es it fr

Tysabri (Antegren) Biogen Brand names, Tysabri (Antegren) Biogen Analogs

Tysabri (Antegren) Biogen Brand Names Mixture

  • No information avaliable

Tysabri (Antegren) Biogen Chemical_Formula

No information avaliable

Tysabri (Antegren) Biogen RX_link


Tysabri (Antegren) Biogen fda sheet

Tysabri (Antegren) Biogen msds (material safety sheet)

Tysabri (Antegren) Biogen Synthesis Reference

Sequence listed in Leger OJ, Yednock TA, Tanner L, Horner HC, Hines DK, Keen S, Saldanha J, Jones ST, Fritz LC, Bendig MM. Humanization of a mouse antibody against human alpha-4 integrin: a potential therapeutic for the treatment of multiple sclerosis. Hum Antibodies. 1997;8(1):3-16

Tysabri (Antegren) Biogen Molecular Weight

No information avaliable

Tysabri (Antegren) Biogen Melting Point

61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

Tysabri (Antegren) Biogen H2O Solubility

No information avaliable

Tysabri (Antegren) Biogen State


Tysabri (Antegren) Biogen LogP

No information avaliable

Tysabri (Antegren) Biogen Dosage Forms

Solution (IV Infusion)

Tysabri (Antegren) Biogen Indication

For treatment of multiple sclerosis

Tysabri (Antegren) Biogen Pharmacology

In multiple sclerosis, lesions are believed to occur when activated inflammatory cells, including T-lymphocytes, cross the blood-brain barrier (BBB). Leukocyte migration across the BBB involves interaction between adhesion molecules on inflammatory cells, and their counter-receptors present on endothelial cells of the vessel wall. The clinical effect of natalizumab in multiple sclerosis may be a secondary result of its blockade of the molecular interaction of a 4b 1-integrin expressed by inflammatory cells with VCAM-1 on vascular endothelial cells, and with CS-1 and/or osteopontin expressed by parenchymal cells in the brain.

Tysabri (Antegren) Biogen Absorption

No information avaliable

Tysabri (Antegren) Biogen side effects and Toxicity

No information avaliable

Tysabri (Antegren) Biogen Patient Information


Tysabri (Antegren) Biogen Organisms Affected

Humans and other mammals