Tygacil
Brand names,
Tygacil
Analogs
Tygacil
Brand Names Mixture
Tygacil
Chemical_Formula
SSe
Tygacil
RX_link
http://www.rxlist.com/cgi/generic2/selsun.htm
Tygacil
fda sheet
Tygacil
msds (material safety sheet)
Tygacil
Synthesis Reference
No information avaliable
Tygacil
Molecular Weight
111.026 g/mol
Tygacil
Melting Point
100 oC
Tygacil
H2O Solubility
Practically insoluble
Tygacil
State
Solid
Tygacil
LogP
No information avaliable
Tygacil
Dosage Forms
Liquid; Lotion; Shampoo; Suspension
Tygacil
Indication
For treatment of tinea versicolor, dandruff and seborrheic dermatitis of the scalp.
Tygacil
Pharmacology
Selenium sulfide is an antifungal agent often used in shampoos for the treatment of dandruff and seborrheic dermatitis. Selenium sulfide is highly active in inhibiting the growth of P. ovale. It is also a proven cytostatic agent, slowing the growth of both hyperproliferative and normal cells in dandruff and seborrheic dermatitis. A 0.6% micronized form of selenium sulfide is also safe and effective for dandruff.
Tygacil
Absorption
There is no substantial absorption through intact skin. Absorption has been reported in patients with open lesions on the scalp or in patients using a 1% cream on the back - a patient with scalp lesions that used selenium shampoos had a level of selenium sulfide as high as 32 μg/ml in her urine.
Tygacil
side effects and Toxicity
No documented reports of serious toxicity in humans resulting from acute ingestion of selenium sulfide, however, acute toxicity studies in animals suggest that ingestion of large amounts could result in potential human toxicity.
Tygacil
Patient Information
Tygacil
Organisms Affected
Humans, other mammals, fungi and bacteria