Tolnaftate
Brand names,
Tolnaftate
Analogs
Tolnaftate
Brand Names Mixture
Tolnaftate
Chemical_Formula
C19H17NOS
Tolnaftate
RX_link
No information avaliable
Tolnaftate
fda sheet
Tolnaftate
msds (material safety sheet)
Tolnaftate
Synthesis Reference
No information avaliable
Tolnaftate
Molecular Weight
307.409 g/mol
Tolnaftate
Melting Point
111 oC
Tolnaftate
H2O Solubility
7.02e-05 mg/mL at 25 oC [MEYLAN,WM et al. (1996)]
Tolnaftate
State
Solid
Tolnaftate
LogP
5.109
Tolnaftate
Dosage Forms
Aerosol (with Propellants); Cream; Gel; Liquid; Powder; Spray; Swab
Tolnaftate
Indication
Tolnaftate topical is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections. Tolnaftate is also used, along with other antifungals, to treat infections of the nails, scalp, palms, and soles of the feet. The powder and powder aerosol may be used to prevent athlete's foot.
Tolnaftate
Pharmacology
Tolnaftate is a synthetic over-the-counter anti-fungal agent.
Tolnaftate
Absorption
No information avaliable
Tolnaftate
side effects and Toxicity
Oral rat LD50: 891 mg/kg. Inhalation rat LC50: > 900 mg/m3/1hr. Irritation: skin rabbit: 500 mg/24H mild. Eye rabbit: 100 mg severe. Investigated a mutagen and reproductive effector.
Tolnaftate
Patient Information
No information avaliable
Tolnaftate
Organisms Affected
Yeast and other fungi