Tofranil, Base

Tofranil, Base Brand names, Tofranil, Base Analogs

Tofranil, Base Brand Names Mixture

No information avaliable

Tofranil, Base Chemical_Formula

C₁₉H₂₄N₂

Tofranil, Base RX_link

http://www.rxlist.com/cgi/generic/imip.htm

Tofranil, Base fda sheet

Tofranil,_Base FDA

Tofranil, Base msds (material safety sheet)

Tofranil, Base Synthesis Reference

No information avaliable

Tofranil, Base Molecular Weight

280.407 g/mol

Tofranil, Base Melting Point

174.5 ^oC

Tofranil, Base H₂O Solubility

18.2 mg/L

Tofranil, Base State

Solid

Tofranil, Base LogP

4.184

Tofranil, Base Dosage Forms

Tablet

Tofranil, Base Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Tofranil, Base Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Tofranil, Base Absorption

Rapidly and well absorbed after oral administration

Tofranil, Base side effects and Toxicity

Oral, rat LD₅₀: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Tofranil, Base Patient Information

Tofranil, Base Organisms Affected

Humans and other mammals