Sulphacetamide
Brand names,
Sulphacetamide
Analogs
Sulphacetamide
Brand Names Mixture
- Ak Cide Oph Soln (Prednisolone Acetate + Sulfacetamide Sodium)
- Blephamide Oph Ont (Prednisolone Acetate + Sulfacetamide Sodium)
- Blephamide Opht Suspension (Prednisolone Acetate + Sulfacetamide Sodium)
- Cocci Bol O Tab Jr (Calcium Carbonate + Charcoal Activated + Cobalt Gluconate + Copper Sulfate + Ferrous Gluconate + Sodium Arsanilate + Sulfabenzamide Sodium + Sulfacetamide Sodium + Sulfaquinoxaline + Tannic Acid)
- Cocci Bol-O-Tab (Calcium Carbonate + Charcoal Activated + Cobalt Gluconate + Copper Sulfate + Ferrous Gluconate + Sodium Arsanilate + Sulfabenzamide Sodium + Sulfacetamide Sodium + Sulfaquinoxaline + Tannic Acid)
- Dioptimyd Ointment (Prednisolone Acetate + Sulfacetamide Sodium)
- Dioptimyd Suspension (Prednisolone Acetate + Sulfacetamide Sodium)
- Medicocci-Jr (Arsenic (Sodium Arsanilate) + Calcium Carbonate + Charcoal Activated + Cobalt Gluconate + Copper Sulfate + Ferrous Gluconate + Sulfabenzamide Sodium + Sulfacetamide Sodium + Sulfaquinoxaline + Tannic Acid)
- Medicocci-Sr (Arsenic (Sodium Arsanilate) + Calcium Carbonate + Charcoal Activated + Cobalt Gluconate + Copper Sulfate + Ferrous Gluconate + Sulfabenzamide Sodium + Sulfacetamide Sodium + Sulfaquinoxaline + Tannic Acid)
- Metimyd Oph Sus (Prednisolone Acetate + Sulfacetamide Sodium)
- Neo Atropec 25 Tab (Aluminum Hydroxide + Atropine Methylnitrate + Kaolin + Neomycin Sulfate + Pectin + Sulfacetamide + Sulfaguanidine)
- Neo Atropec C Tab (Aluminum Hydroxide + Atropine Methylnitrate + Kaolin + Neomycin Sulfate + Pectin + Sulfacetamide + Sulfaguanidine)
- Neo Atropec Tab (Aluminum Hydroxide + Atropine Methylnitrate + Kaolin + Neomycin Sulfate + Pectin + Sulfacetamide + Sulfaguanidine)
- Sulfacet R Lotion (Sulfacetamide Sodium + Sulfur (Sulfur))
- Sulfacet-R Lotion (Sulfacetamide Sodium + Sulfur)
- Sultrin Triple Sulfa Crm (Sulfacetamide + Sulfanilylbenzamide + Sulfathiazole + Urea)
- Vasocidin Ophthalmic Solution (Prednisolone Sodium Phosphate + Sulfacetamide Sodium)
- Vasosulf Oph Soln (Phenylephrine Hydrochloride + Sulfacetamide Sodium)
Sulphacetamide
Chemical_Formula
C8H10N2O3S
Sulphacetamide
RX_link
http://www.rxlist.com/cgi/generic3/plexion.htm
Sulphacetamide
fda sheet
Sulphacetamide
msds (material safety sheet)
Sulphacetamide
Synthesis Reference
No information avaliable
Sulphacetamide
Molecular Weight
214.243 g/mol
Sulphacetamide
Melting Point
183 oC
Sulphacetamide
H2O Solubility
1.25E+004 mg/L
Sulphacetamide
State
Solid
Sulphacetamide
LogP
0.201
Sulphacetamide
Dosage Forms
Drops; Liquid; Ointment
Sulphacetamide
Indication
For the treatment of bacterial vaginitis, keratitis, acute conjunctivitis, and blepharitis.
Sulphacetamide
Pharmacology
Sulfacetamide is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulphacetamide
Absorption
No information avaliable
Sulphacetamide
side effects and Toxicity
Oral LD50 Mouse : 16500 mg/kg. Side effects include moderate to severe erythema (redness) and moderate edema (raised kin), nausea, vomiting, headache, dizziness, and tiredness. Higher exposure causes unconsciousness.
Sulphacetamide
Patient Information
To avoid contamination, do not touch lip of container to eye, eyelid or any surface.
Sulphacetamide
Organisms Affected
Enteric bacteria and other eubacteria