Spectinomycin
Brand names,
Spectinomycin
Analogs
Spectinomycin
Brand Names Mixture
Spectinomycin
Chemical_Formula
C14H24N2O7
Spectinomycin
RX_link
http://www.rxlist.com/cgi/generic/trobicin.htm
Spectinomycin
fda sheet
Spectinomycin
msds (material safety sheet)
Spectinomycin
Synthesis Reference
No information avaliable
Spectinomycin
Molecular Weight
332.35 g/mol
Spectinomycin
Melting Point
No information avaliable
Spectinomycin
H2O Solubility
Easily soluble in cold water
Spectinomycin
State
Solid
Spectinomycin
LogP
-2.88
Spectinomycin
Dosage Forms
Sterile powder for injectable suspension
Spectinomycin
Indication
For use in the treatment of acute gonorrheal urethritis and proctitis in the male and acute gonorrheal cervicitis and proctitis in the female when due to susceptible strains of Neisseria gonorrhoeae.
Spectinomycin
Pharmacology
Spectinomycin is an aminocyclitol antibiotic produced by a species of soil microorganism designated as Streptomyces spectabilis. In vitro studies have shown spectinomycin to be active against most strains of Neisseria gonorrhoeae (minimum inhibitory concentration <7.5 to 20 mcg/mL). Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure.
Spectinomycin
Absorption
Rapidly and almost completely absorbed after intramuscular injection.
Spectinomycin
side effects and Toxicity
Acute oral toxicity (LD50): >5000 mg/kg [Rat]. Information on overdosage in humans is not available.
Spectinomycin
Patient Information
No information avaliable
Spectinomycin
Organisms Affected
Enteric bacteria and other eubacteria