Sandostatin LAR
Brand names,
Sandostatin LAR
Analogs
Sandostatin LAR
Brand Names Mixture
Sandostatin LAR
Chemical_Formula
C49H66N10O10S2.2C2H4O2
Sandostatin LAR
RX_link
http://www.rxlist.com/cgi/generic2/octreotide.htm
Sandostatin LAR
fda sheet
Sandostatin LAR
msds (material safety sheet)
Sandostatin LAR
Synthesis Reference
No information avaliable
Sandostatin LAR
Molecular Weight
1138.4822
Sandostatin LAR
Melting Point
No information avaliable
Sandostatin LAR
H2O Solubility
No information avaliable
Sandostatin LAR
State
Liquid
Sandostatin LAR
LogP
No information avaliable
Sandostatin LAR
Dosage Forms
Solution
Sandostatin LAR
Indication
For treatment of acromegaly and reduction of side effects from cancer chemotherapy
Sandostatin LAR
Pharmacology
Octreotide exerts pharmacologic actions similar to the natural hormone, somatostatin. It is an even more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Like somatostatin, it also suppresses leuteinizing hormone (LH) response to GnRH, decreases splanchnic blood flow, and inhibits release of serotonin, gastrin, vasoactive intestinal peptide, secretin, motilin, and pancreatic polypeptide. Octreotide has been used to treat the symptoms associated with metastatic carcinoid tumors (flushing and diarrhea), and Vasoactive Intestinal Peptide (VIP) secreting adenomas (watery diarrhea). Octreotide substantially reduces and in many cases can normalize growth hormone and/or IGF-1 (somatomedin C) levels in patients with acromegaly.
Sandostatin LAR
Absorption
No information avaliable
Sandostatin LAR
side effects and Toxicity
No information avaliable
Sandostatin LAR
Patient Information
No information avaliable
Sandostatin LAR
Organisms Affected
Humans and other mammals