Rulide
Rulide Brand names, Rulide Analogs
Rulide Brand Names Mixture
- No information avaliable
Rulide Chemical_Formula
C40H48I2N2O6
Rulide RX_link
No information avaliable
Rulide fda sheet
Rulide msds (material safety sheet)
Rulide Synthesis Reference
No information avaliable
Rulide Molecular Weight
906.628 g/mol
Rulide Melting Point
257 to 267 oC (decomposes with the evolution of gas)
Rulide H2O Solubility
No information avaliable
Rulide State
Solid
Rulide LogP
No information avaliable
Rulide Dosage Forms
Liquid (for injection)
Rulide Indication
For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
Rulide Pharmacology
Metocurine iodide is a benzylisoquinolinium competitive nondepolarizing neuromuscular blocking agent. Metocurine iodide has a moderate risk of inducing histamine release and has some ganglion blocking activity. Metocurine iodide can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation. As with other nondepolarizing neuromuscular blockers, the time to onset of paralysis decreases and the duration of maximum effect increases with increasing doses of metocurine iodide. Repeated administration of maintenance doses of metocurine iodide has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing. Moreover, the time needed to recover from repeat doses does not change with additional doses. Repeat doses can therefore be administered at relatively regular intervals with predictable results.
Rulide Absorption
No information avaliable
Rulide side effects and Toxicity
Excessive doses can be expected to produce enhanced pharmacological effects. Overdosage may increase the risk of histamine release and cardiovascular effects, especially hypotension.
Rulide Patient Information
No information avaliable
Rulide Organisms Affected
Humans and other mammals
