Ramelteon
Brand names,
Ramelteon
Analogs
Ramelteon
Brand Names Mixture
Ramelteon
Chemical_Formula
C16H21NO2
Ramelteon
RX_link
http://www.rxlist.com/cgi/generic4/rozerem.htm
Ramelteon
fda sheet
Ramelteon
msds (material safety sheet)
Ramelteon
Synthesis Reference
No information avaliable
Ramelteon
Molecular Weight
259.343 g/mol
Ramelteon
Melting Point
No information avaliable
Ramelteon
H2O Solubility
No information avaliable
Ramelteon
State
No information avaliable
Ramelteon
LogP
2.536
Ramelteon
Dosage Forms
No information avaliable
Ramelteon
Indication
For the treatment of insomnia characterized by difficulty with sleep onset.
Ramelteon
Pharmacology
Ramelton is the first selective melatonin agonist. It works by mimicing melatonin (MT), a naturally occuring hormone that is produced during the sleep period. It has a high affinity for the MT1 and MT2 receptor. The MT1 and MT2 receptors are located in the brain's suprachiasmatic nuclei (SCN). The SCN is known as the body's "master clock" because it regulates the 24-hour sleep-wake cycle. Ramelton has an active metabolite that is less potent but circulates in higher concentrations than the parent compound. The metabolite also has weak affinity for the 5HT2b receptor.
Ramelteon
Absorption
Rapid, total absorption is at least 84%.
Ramelteon
side effects and Toxicity
No information avaliable
Ramelteon
Patient Information
Ramelteon
Organisms Affected
Humans and other mammals