Rabeprazole
Brand names,
Rabeprazole
Analogs
Rabeprazole
Brand Names Mixture
Rabeprazole
Chemical_Formula
C18H21N3O3S
Rabeprazole
RX_link
http://www.rxlist.com/cgi/generic3/aciphex.htm
Rabeprazole
fda sheet
Rabeprazole
msds (material safety sheet)
Rabeprazole
Synthesis Reference
No information avaliable
Rabeprazole
Molecular Weight
359.444 g/mol
Rabeprazole
Melting Point
No information avaliable
Rabeprazole
H2O Solubility
No information avaliable
Rabeprazole
State
No information avaliable
Rabeprazole
LogP
1.177
Rabeprazole
Dosage Forms
Tablet (enteric-coated)
Rabeprazole
Indication
For short-term treatment in the healing and symptomatic relief of erosive or ulcerative gastroesophageal reflux disease (GERD).
Rabeprazole
Pharmacology
Rabeprazole prevents the production of acid in the stomach. It reduces symptoms and prevents injury to the esophagus or stomach in patients with gastroesophageal reflux disease (GERD) or ulcers. Rabeprazole is also useful in conditions that produce too much stomach acid such as Zollinger-Ellison syndrome. Rabeprazole may also be used with antibiotics to get rid of bacteria that are associated with some ulcers. Rabeprazole is a selective and irreversible proton pump inhibitor, suppresses gastric acid secretion by specific inhibition of the H+, K+ -ATPase enzyme system which is found at the secretory surface of parietal cells. It inhibits the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen.
Rabeprazole
Absorption
Absolute bioavailability is approximately 52%.
Rabeprazole
side effects and Toxicity
No information avaliable
Rabeprazole
Patient Information
No information avaliable
Rabeprazole
Organisms Affected
Humans and other mammals