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Primachin Brand names, Primachin Analogs

Primachin Brand Names Mixture

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Primachin Chemical_Formula


Primachin RX_link

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Primachin fda sheet

Primachin FDA

Primachin msds (material safety sheet)

Primachin Synthesis Reference

No information avaliable

Primachin Molecular Weight

259.347 g/mol

Primachin Melting Point

< 25 oC

Primachin H2O Solubility

No information avaliable

Primachin State


Primachin LogP


Primachin Dosage Forms


Primachin Indication

For the treatment of malaria.

Primachin Pharmacology

Primaquine is an antimalarial agent and is the essential co-drug with chloroquine in treating all cases of malaria. In the blood, malaria parasites break down a part of the red blood cells known as haemoglobin. When this happens haemoglobin is divided into two parts; haem and globin. Haem is toxic to the malaria parasite. To prevent it from being damaged, the malaria parasite produces an chemical which converts the toxic haem into a non-toxic product. Primaquine acts by interfering with a part of the parasite (mitochondria) that is responsible for supplying it with energy. Without energy the parasite dies. This stops the infection from continuing and allows the person to recover. Primaquine kills the intrahepatic form of Plasmodium vivax and Plasmodium ovale, and thereby prevents the development of the erythrocytic forms that are responsible for relapses (it also kills gametocytes). Primaquine is not used in the prevention of malaria, only in the treatment. It has insignificant activity against the asexual blood forms of the parasite and therefore it is always used in conjunction with a blood schizonticide and never as a single agent. Primaquine has gametocytocidal activity against all plasmodia, including P. falciparum.

Primachin Absorption

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Primachin side effects and Toxicity

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Primachin Patient Information

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Primachin Organisms Affected