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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C25H45N3O16
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RX_link
http://www.rxlist.com/cgi/generic/acarbose.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
643.635 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
Solid
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LogP
-8.832
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Dosage Forms
Tablet
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Indication
For treatment and management of diabetes type II (used in combination therapy as a second or third line agent)
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Pharmacology
Used to reduce blood gluose in patients with type 2 diabetes. Acarbose is a complex oligosaccharide that delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following meals. Acarbose binds to and inhibits alpha amylase and alpha-gluocside hydrolases. In diabetic patients, this enzyme inhibition results in a delayed glucose absorption and a lowering of postprandial hyperglycemia.
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Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals