Pegfilgrastim
Brand names,
Pegfilgrastim
Analogs
Pegfilgrastim
Brand Names Mixture
Pegfilgrastim
Chemical_Formula
C845H1343N223O243S9
Pegfilgrastim
RX_link
http://www.rxlist.com/cgi/generic3/neulasta.htm
Pegfilgrastim
fda sheet
Pegfilgrastim
msds (material safety sheet)
Pegfilgrastim
Synthesis Reference
No information avaliable
Pegfilgrastim
Molecular Weight
18802.8
Pegfilgrastim
Melting Point
60 oC (Luo, P., Protein Science 11:1218-1226 (2002))
Pegfilgrastim
H2O Solubility
No information avaliable
Pegfilgrastim
State
Liquid
Pegfilgrastim
LogP
0.209
Pegfilgrastim
Dosage Forms
Solution
Pegfilgrastim
Indication
Increases leukocyte production, for treatment in non-myeloid cancer, neutropenia and bone marrow transplant
Pegfilgrastim
Pharmacology
Used in the treatment of chemotherapy-induced neutropenia by enhancing the production of neutrophils. Pegfilgrastim acts on hematopoietic cells by binding to specific cell surface receptors thereby stimulating proliferation, differentiation, commitment, and end cell functional activation. Pegfilgrastim has reduced renal clearance and prolonged persistence in vivo as compared to Filgrastim.
Pegfilgrastim
Absorption
No information avaliable
Pegfilgrastim
side effects and Toxicity
No information avaliable
Pegfilgrastim
Patient Information
BIOD00094.html
Pegfilgrastim
Organisms Affected
No information avaliable