PGI2
Brand names,
PGI2
Analogs
PGI2
Brand Names Mixture
PGI2
Chemical_Formula
C16H25NO4
PGI2
RX_link
http://www.rxlist.com/cgi/generic3/esmolol.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
295.374 g/mol
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Melting Point
No information avaliable
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H2O Solubility
Very soluble as hydrochloride salt
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State
Solid
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LogP
2.41
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Dosage Forms
Liquid
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Indication
For the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention.
PGI2
Pharmacology
No information avaliable
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Absorption
Rapidly absorbed, steady-state blood levels for dosages from 50-300 µg/kg/min (0.05-0.3 mg/kg/mm) are obtained within five minutes.
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side effects and Toxicity
Symptoms of overdose include cardiac arrest, bradycardia, hypotension, electromechanical dissociation and loss of consciousness.
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Patient Information
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Organisms Affected
Humans and other mammals