Mononitrogen monoxide
Brand names,
Mononitrogen monoxide
Analogs
Mononitrogen monoxide
Brand Names Mixture
- Aldoril 15 Tab (Hydrochlorothiazide + Methyldopa)
- Aldoril 25 Tab (Hydrochlorothiazide + Methyldopa)
- Apo Methazide 15 (Hydrochlorothiazide + Methyldopa)
- Apo Methazide 25 (Hydrochlorothiazide + Methyldopa)
- Novo-Doparil 15 Tab (Hydrochlorothiazide + Methyldopa)
- Novo-Doparil 25 Tab (Hydrochlorothiazide + Methyldopa)
- Pms-Dopazide 15 Tab (Hydrochlorothiazide + Methyldopa)
- Pms-Dopazide-25 Tab (Hydrochlorothiazide + Methyldopa)
- Supres 150 Tab (Chlorothiazide + Methyldopa)
- Supres 250 Tab (Chlorothiazide + Methyldopa)
Mononitrogen monoxide
Chemical_Formula
NO
Mononitrogen monoxide
RX_link
http://www.rxlist.com/cgi/generic/inomax.htm
Mononitrogen monoxide
fda sheet
Mononitrogen monoxide
msds (material safety sheet)
Mononitrogen monoxide
Synthesis Reference
No information avaliable
Mononitrogen monoxide
Molecular Weight
30.0061 g/mol
Mononitrogen monoxide
Melting Point
-163.6 oC
Mononitrogen monoxide
H2O Solubility
9.49E+004 mg/L
Mononitrogen monoxide
State
Liquid
Mononitrogen monoxide
LogP
0.10
Mononitrogen monoxide
Dosage Forms
Cream; Drops; Gas; Liquid; Lotion; Ointment; Powder; Tablet
Mononitrogen monoxide
Indication
For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
Mononitrogen monoxide
Pharmacology
Persistent pulmonary hypertension of the newborn (PPHN) occurs as a primary developmental defect or as a condition secondary to other diseases such as meconium aspiration syndrome (MAS), pneumonia, sepsis, hyaline membrane disease, congenital diaphragmatic hernia (CDH), and pulmonary hypoplasia. In these states, pulmonary vascular resistance (PVR) is high, which results in hypoxemia secondary to right-to-left shunting of blood through the patent ductus arteriosus and foramen ovale. In neonates with PPHN, Nitric oxide improves oxygenation (as indicated by significant increases in PaO2). Nitric oxide appears to increase the partial pressure of arterial oxygen (PaO2) by dilating pulmonary vessels in better entilated areas of the lung, redistributing pulmonary blood flow away from lung regions with low ventilation/perfusion (V/Q) ratios toward regions with normal ratios.
Mononitrogen monoxide
Absorption
Nitric oxide is absorbed systemically after inhalation.
Mononitrogen monoxide
side effects and Toxicity
No information avaliable
Mononitrogen monoxide
Patient Information
No information avaliable
Mononitrogen monoxide
Organisms Affected
Humans and other mammals