Metossamina [DCIT]
Brand names,
Metossamina [DCIT]
Analogs
Metossamina [DCIT]
Brand Names Mixture
Metossamina [DCIT]
Chemical_Formula
C11H17NO3
Metossamina [DCIT]
RX_link
No information avaliable
Metossamina [DCIT]
fda sheet
Metossamina [DCIT]
msds (material safety sheet)
Metossamina [DCIT]
Synthesis Reference
No information avaliable
Metossamina [DCIT]
Molecular Weight
211.258 g/mol
Metossamina [DCIT]
Melting Point
No information avaliable
Metossamina [DCIT]
H2O Solubility
Soluble (185 g/L)
Metossamina [DCIT]
State
Solid
Metossamina [DCIT]
LogP
1.5
Metossamina [DCIT]
Dosage Forms
Liquid
Metossamina [DCIT]
Indication
Indicated for the treatment and management of hypotension.
Metossamina [DCIT]
Pharmacology
Methoxamine is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Methoxamine is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Methoxamine acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.
Metossamina [DCIT]
Absorption
No information avaliable
Metossamina [DCIT]
side effects and Toxicity
No information avaliable
Metossamina [DCIT]
Patient Information
No information avaliable
Metossamina [DCIT]
Organisms Affected
Humans and other mammals