Meclofenamate

Meclofenamate Brand names, Meclofenamate Analogs

Meclofenamate Brand Names Mixture

No information avaliable

Meclofenamate Chemical_Formula

C₁₄H₁₁Cl₂NO₂

Meclofenamate RX_link

http://www.rxlist.com/cgi/generic3/meclofen.htm

Meclofenamate fda sheet

Meclofenamate msds (material safety sheet)

Meclofenamate MSDS

Meclofenamate Synthesis Reference

No information avaliable

Meclofenamate Molecular Weight

295.02 g/mol

Meclofenamate Melting Point

257 ^oC

Meclofenamate H₂O Solubility

30 mg/L

Meclofenamate State

Solid

Meclofenamate LogP

4.998

Meclofenamate Dosage Forms

Capsules (containing 50 mg or 100 mg meclofenamic acid as the sodium salt)

Meclofenamate Indication

For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.

Meclofenamate Pharmacology

Meclofenamate is a nonsteroidal agent which has demonstrated anti-inflammatory, analgesic, and antipyretic activity in laboratory animals.

Meclofenamate Absorption

Rapidly absorbed in man following single and multiple oral doses with peak plasma concentrations occurring in 0.5 to 2 hours. The concomitant administration of antacids (aluminum and magnesium hydroxides) does not interfere with absorption of meclofenamate. Unlike most NSAIDs, which when administered with food have a decrease in rate but not in extent of absorption, meclofenamic acid is decreased in both. It has been reported that following the administration of meclofenamate capsules one-half hour after a meal, the average extent of bioavailability decreased by 26%, the average peak concentration (C_max) decreased fourfold and the time to C_max was delayed by 3 hours.

Meclofenamate side effects and Toxicity