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Malathion Brand names, Malathion Analogs

Malathion Brand Names Mixture

  • Nupercainal Antiseptic Crm (Dibucaine + Domiphen Bromide)
  • Proctol Ointment (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctol Suppositories (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctosedyl Ointment (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctosedyl Sup (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctosedyl Suppositories (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Proctosone Ont (Dibucaine Hydrochloride + Esculin + Hydrocortisone Acetate + Neomycin Sulfate)
  • Proctosone Sup (Dibucaine Hydrochloride + Esculin + Hydrocortisone Acetate + Neomycin Sulfate)
  • Ratio-Proctosone (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone (Hydrocortisone Acetate))
  • Sab-Proctomyxin Hc Suppositories (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)
  • Sandoz Proctomyxin Hc (Dibucaine Hydrochloride + Esculin + Framycetin Sulfate + Hydrocortisone)

Malathion Chemical_Formula

C10H19O6PS2

Malathion RX_link

http://www.rxlist.com/cgi/generic3/ovide.htm

Malathion fda sheet

Malathion FDA

Malathion msds (material safety sheet)

Malathion MSDS

Malathion Synthesis Reference

No information avaliable

Malathion Molecular Weight

330.36 g/mol

Malathion Melting Point

2.8 oC

Malathion H2O Solubility

143 mg/L

Malathion State

Liquid

Malathion LogP

2.36

Malathion Dosage Forms

Topical solution; Lotion

Malathion Indication

For patients infected with Pediculus humanus capitis (head lice and their ova) of the scalp hair.

Malathion Pharmacology

Malathion is an organophosphate insecticide commonly used to control mosquitos and other flying insects. Pharmaceutically, malathion is used to eliminate head lice. The principal toxicological effect of malathion is cholinesterase inhibition, due primarily to malaoxon and to phosphorus thionate impurities.

Malathion Absorption

Malathion in an acetone vehicle has been reported to be absorbed through normal human skin only to the extent of 8% of the applied dose. Absorption may be increased when malathion is applied to damaged skin. Malathion is rapidly and effectively absorbed by practically all routes including the gastrointestinal tract, skin, mucous membranes, and lungs. However, it is readily excreted in the urine, and does not accumulate in organs or tissues.

Malathion side effects and Toxicity

Malathion is slightly toxic via the oral route, with reported oral LD50 values of 1000 mg/kg to greater than 10,000 mg/kg in the rat. It is also slightly toxic via the dermal route, with reported dermal LD50 values of greater than 4000 mg/kg in rats. Moderate poisoning can result in chest tightness, difficulty breathing, bradycardia, tachycardia, tremor/ataxia, blurred vision, and confusion. Severe, life-threatening signs include coma, seizures, respiratory arrest, and paralysis. Malathion may also be irritating to the skin and eyes.

Malathion Patient Information

Malathion Organisms Affected

Head lice