Lercanidipine
Lercanidipine Brand names, Lercanidipine Analogs
Lercanidipine Brand Names Mixture
- No information avaliable
Lercanidipine Chemical_Formula
C36H41N3O6
Lercanidipine RX_link
No information avaliable
Lercanidipine fda sheet
Lercanidipine msds (material safety sheet)
Lercanidipine Synthesis Reference
No information avaliable
Lercanidipine Molecular Weight
611.727 g/mol
Lercanidipine Melting Point
No information avaliable
Lercanidipine H2O Solubility
No information avaliable
Lercanidipine State
Solid
Lercanidipine LogP
7.16
Lercanidipine Dosage Forms
No information avaliable
Lercanidipine Indication
For the treatment of Hypertension and management of angina pectoris and Raynaud's syndrome
Lercanidipine Pharmacology
Lercanidipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Lercanidipine is similar to other peripheral vasodilators. Lercanidipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Lercanidipine Absorption
No information avaliable
Lercanidipine side effects and Toxicity
No information avaliable
Lercanidipine Patient Information
No information avaliable
Lercanidipine Organisms Affected
Humans and other mammals
