Ketorolac
Brand names,
Ketorolac
Analogs
Ketorolac
Brand Names Mixture
Ketorolac
Chemical_Formula
C15H13NO3
Ketorolac
RX_link
http://www.rxlist.com/cgi/generic/ketor.htm
Ketorolac
fda sheet
Ketorolac
msds (material safety sheet)
Ketorolac
Synthesis Reference
No information avaliable
Ketorolac
Molecular Weight
255.269 g/mol
Ketorolac
Melting Point
165-167 oC (tromethamine salt)
Ketorolac
H2O Solubility
25 mg/mL (tromethamine salt)
Ketorolac
State
Solid
Ketorolac
LogP
2.236
Ketorolac
Dosage Forms
Liquid; Solution; Tablet
Ketorolac
Indication
For the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting.
Ketorolac
Pharmacology
Ketorolac, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. It is a peripherally acting analgesic. The biological activity of ketorolac tromethamine is associated with the S-form. Ketorolac tromethamine possesses no sedative or anxiolytic properties.
Ketorolac
Absorption
Rapidly and completely absorbed after oral administration
Ketorolac
side effects and Toxicity
LD50 = 189 mg/kg (rat, oral).
Ketorolac
Patient Information
Ketorolac
Organisms Affected
Humans and other mammals