Ketoprofen
Brand names,
Ketoprofen
Analogs
Ketoprofen
Brand Names Mixture
Ketoprofen
Chemical_Formula
C16H14O3
Ketoprofen
RX_link
http://www.rxlist.com/cgi/generic/ketoprof.htm
Ketoprofen
fda sheet
Ketoprofen
msds (material safety sheet)
Ketoprofen
Synthesis Reference
No information avaliable
Ketoprofen
Molecular Weight
254.281 g/mol
Ketoprofen
Melting Point
94 oC
Ketoprofen
H2O Solubility
51 mg/L
Ketoprofen
State
Solid
Ketoprofen
LogP
3.556
Ketoprofen
Dosage Forms
Capsule; Capsule (sustained-release); Suppository; Tablet; Tablet (enteric-coated); Tablet (extended-release)
Ketoprofen
Indication
For the treatment of pain (muscular and rheumatic), sprains, strains, backache and neuralgia and for the management of the signs and symptoms of rheumatoid arthritis and osteoarthritis.
Ketoprofen
Pharmacology
Ketoprofen is a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Ketoprofen has pharmacologic actions similar to those of other prototypical NSAIDs, that is thought to be associated with the inhibition of prostaglandin synthesis. Ketoprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.
Ketoprofen
Absorption
Ketoprofen is rapidly and well-absorbed orally, with peak plasma levels occurring within 0.5 to 2 hours.
Ketoprofen
side effects and Toxicity
LD50=62.4 mg/kg (rat, oral) Adverse effects from overdose include breathing difficulty, coma, convulsions, drowsiness, high blood pressure, kidney failure, low blood pressure, nausea, sluggishness, stomach and intestinal bleeding, stomach pain, vomiting.
Ketoprofen
Patient Information
Ketoprofen
Organisms Affected
Humans and other mammals