Irsogladine Maleate en es it fr

Irsogladine Maleate Brand names, Irsogladine Maleate Analogs

Irsogladine Maleate Brand Names Mixture

  • No information avaliable

Irsogladine Maleate Chemical_Formula

C12H21N

Irsogladine Maleate RX_link

http://www.rxlist.com/cgi/generic/rimantadine.htm

Irsogladine Maleate fda sheet

Irsogladine_Maleate FDA

Irsogladine Maleate msds (material safety sheet)

Irsogladine_Maleate MSDS

Irsogladine Maleate Synthesis Reference

No information avaliable

Irsogladine Maleate Molecular Weight

179.302 g/mol

Irsogladine Maleate Melting Point

>300oC

Irsogladine Maleate H2O Solubility

Hydrochloride salt freely soluble (50 mg/ml at 20°C)

Irsogladine Maleate State

Solid

Irsogladine Maleate LogP

2.374

Irsogladine Maleate Dosage Forms

Available as 100 mg film-coated tablets and as syrup for oral administration.

Irsogladine Maleate Indication

For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults.

Irsogladine Maleate Pharmacology

Rimantadine, a cyclic amine, is a synthetic antiviral drug and a derivate of adamantane, like a similar drug amantadine. Rimantadine is inhibitory to the in vitro replication of influenza A virus isolates from each of the three antigenic subtypes (H1N1, H2H2 and H3N2) that have been isolated from man. Rimantadine has little or no activity against influenza B virus. Rimantadine does not appear to interfere with the immunogenicity of inactivated influenza A vaccine.

Irsogladine Maleate Absorption

Well absorbed, with the tablet and syrup formulations being equally absorbed after oral administration.

Irsogladine Maleate side effects and Toxicity

Oral LD50 in rats is 640 mg/kg. Overdoses of a related rug, amantadine, have been reported with adverse reactions consisting of agitation, hallucinations, cardiac arrhythmia and death.

Irsogladine Maleate Patient Information

Irsogladine Maleate Organisms Affected

Human Influenza A Virus