Intron A (Schering Corp)
Brand names,
Intron A (Schering Corp)
Analogs
Intron A (Schering Corp)
Brand Names Mixture
Intron A (Schering Corp)
Chemical_Formula
C860H1353N229O255S9
Intron A (Schering Corp)
RX_link
http://www.rxlist.com/cgi/generic2/ribav.htm
Intron A (Schering Corp)
fda sheet
Intron A (Schering Corp)
msds (material safety sheet)
Intron A (Schering Corp)
Synthesis Reference
No information avaliable
Intron A (Schering Corp)
Molecular Weight
19269.1
Intron A (Schering Corp)
Melting Point
61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999))
Intron A (Schering Corp)
H2O Solubility
No information avaliable
Intron A (Schering Corp)
State
Liquid
Intron A (Schering Corp)
LogP
-0.339
Intron A (Schering Corp)
Dosage Forms
Solution (Injection); Powder for Injection
Intron A (Schering Corp)
Indication
For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma
Intron A (Schering Corp)
Pharmacology
Upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase) and protein kinase R.
Intron A (Schering Corp)
Absorption
No information avaliable
Intron A (Schering Corp)
side effects and Toxicity
No information avaliable
Intron A (Schering Corp)
Patient Information
BIOD00066.html
Intron A (Schering Corp)
Organisms Affected
No information avaliable