Histalog
Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C5H9N3
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
111.145 g/mol
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Melting Point
< 25 oC
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H2O Solubility
No information avaliable
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State
Liquid
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LogP
0.069
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Dosage Forms
Injection
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Indication
For use clinically to test gastric secretory function.
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Pharmacology
Betazole is a histamine H2 agonist used in a test for measuring maximal production of gastric acidity or anacidity. This measurement can be used to diagnose diseases such as Zollinger-Ellison syndrome, whereby the volume of gastric and basal secretions is measured following betazole administration (greater than 60% of the maximal acid secretion following betazole stimulation). In another test, gastritis can be diagnosed given late absence of gastric acid which is unresponsive to betazole stimulation. Betazole can be used as a gastric secretory stimulant instead of histamine with the advantage of not provoking side effects and thus not requiring the use of antihistaminic compounds.
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Absorption
Rapid and complete.
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals