PharmacyCodes



Ertaczo en es it fr

Ertaczo Brand names, Ertaczo Analogs

Ertaczo Brand Names Mixture

  • No information avaliable

Ertaczo Chemical_Formula

C20H15Cl3N2OS

Ertaczo RX_link

http://www.rxlist.com/cgi/generic3/ertaczo.htm

Ertaczo fda sheet

Ertaczo FDA

Ertaczo msds (material safety sheet)

Ertaczo Synthesis Reference

No information avaliable

Ertaczo Molecular Weight

437.77 g/mol

Ertaczo Melting Point

No information avaliable

Ertaczo H2O Solubility

Practically insoluble

Ertaczo State

Solid

Ertaczo LogP

5.952

Ertaczo Dosage Forms

Cream (2% contains 17.5 mg of sertaconazole)

Ertaczo Indication

For the topical treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.

Ertaczo Pharmacology

Sertaconazole is an imidazole/triazole type antifungal agent. Sertaconazole is a highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethylation via the inhibition of the enzyme cytochrome P450 14α-demethylase. This enzyme converts lanosterol to ergosterol, and is required in fungal cell wall synthesis. The subsequent loss of normal sterols correlates with the accumulation of 14 α-methyl sterols in fungi and may be partly responsible for the fungistatic activity of fluconazole. Mammalian cell demethylation is much less sensitive to fluconazole inhibition. Sertaconazole exhibits in vitro activity against Cryptococcus neoformans and Candida spp. Fungistatic activity has also been demonstrated in normal and immunocompromised animal models for systemic and intracranial fungal infections due to Cryptococcus neoformans and for systemic infections due to Candida albicans.

Ertaczo Absorption

No information avaliable

Ertaczo side effects and Toxicity

No information avaliable

Ertaczo Patient Information

The patient should be instructed to:
  1. Use Sertaconazole Cream, 2%, as directed by the physician. The hands should be washed after applying the medication to the affected area(s). Avoid contact with the eyes, nose, mouth and other mucous membranes. Sertaconazole Cream, 2%, is for external use only.
  2. Dry the affected area(s) thoroughly before application, if you wish to use Sertaconazole Cream, 2%, after bathing.
  3. Use the medication for the full treatment time recommended by the physician, even though symptoms may have improved. Notify the physician if there is no improvement after the end of the prescribed treatment period, or sooner, if the condition worsens.
  4. Inform the physician if the area of application shows signs of increased irritation, redness, itching, burning, blistering, swelling or oozing.
  5. Avoid the use of occlusive dressings unless otherwise directed by the physician.
  6. Do not use this medication for any disorder other than that for which it was prescribed.

Ertaczo Organisms Affected

Yeast and other fungi