Emadine
Emadine Brand names, Emadine Analogs
Emadine Brand Names Mixture
- No information avaliable
Emadine Chemical_Formula
C22H23N3O4
Emadine RX_link
http://www.rxlist.com/cgi/generic4/tarceva.htm
Emadine fda sheet
Emadine msds (material safety sheet)
Emadine Synthesis Reference
No information avaliable
Emadine Molecular Weight
393.436 g/mol
Emadine Melting Point
No information avaliable
Emadine H2O Solubility
Very slightly soluble (hydrochloride salt - maximal solubility of approximately 0.4 mg/mL occurs at a pH of approximately 2)
Emadine State
Solid
Emadine LogP
3.126
Emadine Dosage Forms
Tablet (27.3 mg, 109.3 mg or 163.9 mg)
Emadine Indication
For the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen. Also for use, in combination with gemcitabine, as the first-line treatment of patients with locally advanced, unresectable or metastatic pancreatic cancer.
Emadine Pharmacology
Erlotinib is a Human Epidermal Growth Factor Receptor Type 1/Epidermal Growth Factor Receptor (HER1/EGFR) tyrosine kinase inhibitor.
Emadine Absorption
Erlotinib is about 60% absorbed after oral administration and its bioavailability is substantially increased by food to almost 100%.
Emadine side effects and Toxicity
Symptoms of overdose include diarrhea, rash, and liver transaminase elevation.
Emadine Patient Information
Emadine Organisms Affected
Humans and other mammals
