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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C5H9N1O4
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
147.130 g/mol
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Melting Point
205 oC
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H2O Solubility
No information avaliable
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State
Solid, white crystalline powder
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LogP
-1.43 +/- 0.31
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Dosage Forms
No information avaliable
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Indication
In addition to being one of the building blocks in protein synthesis, it is the most widespread neurotransmitter in brain function, as an excitatory neurotransmitter and as a precursor for the synthesis of GABA in GABAergic neurons.
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Pharmacology
Considered to be nature's "Brain food" by improving mental capacities; helps speed the healing of ulcers; gives a "lift" from fatigue; helps control alcoholism, schizophrenia and the craving for sugar.
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Absorption
Absorbed from the lumen of the small intestine into the enterocytes.Absorption is efficient and occurs by an active transport mechanism.
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side effects and Toxicity
Glutamate causes neuronal damage and eventual cell death, particularly when NMDA receptors are activated, High dosages of glutamic acid may include symptoms such as headaches and neurological problems.
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Patient Information
It is an important excitatory neurotransmitter, and glutamic acid is also important in the metabolism of sugars and fats. It helps with the transportation of potassium across the blood-brain barrier, although itself does not pass this barrier that easily. It also shows promise in the future treatment of neurological conditions, ulcers, hypoglycemic come, muscular dystrophy, epilepsy, Parkinson's, and mental retardation. Glutamic acid can be used as fuel in the brain, and can attach itself to nitrogen atoms in the process of forming glutamine, and this action also detoxifies the body of ammonia. This action is the only way in which the brain can be detoxified from ammonia. The fluid produced by the prostate gland also contains amounts of glutamic acid, and may play a role in the normal function of the prostate.
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Organisms Affected
Humans and other mammals