EPA
EPA Brand names, EPA Analogs
EPA Brand Names Mixture
- No information avaliable
EPA Chemical_Formula
C20H30O2
EPA RX_link
No information avaliable
EPA fda sheet
EPA msds (material safety sheet)
EPA Synthesis Reference
No information avaliable
EPA Molecular Weight
302.456 g/mol
EPA Melting Point
No information avaliable
EPA H2O Solubility
No information avaliable
EPA State
Oily Liquid
EPA LogP
6.23 +/- 0.48
EPA Dosage Forms
Capsule (usually in fish oil in a combination with DHA)
EPA Indication
EPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy.
EPA Pharmacology
Eicosanoids are chemical messengers derived from 20-carbon polyunsaturated fatty acids that play critical roles in immune and inflammatory responses. Both 20-carbon omega-6 fatty acids (arachidonic acid) and 20-carbon omega-3 fatty acids (EPA) can be found in cell membranes. During an inflammatory response, arachidonic acid and EPA are metabolized by enzymes known as cyclooxygenases and lipoxygenases to form eicosanoids. Increasing omega-3 fatty acid intake increases the EPA content of cell membranes and decreases the arachidonic acid content, resulting in higher proportions of eicosanoids derived from EPA. Physiologic responses to arachidonic acid-derived eicosanoids differ from responses to EPA-derived eicosanoids. In general, eicosanoids derived from EPA are less potent inducers of inflammation, blood vessel constriction, and clotting than eicosanoids derived from arachidonic acid.
EPA Absorption
No information avaliable
EPA side effects and Toxicity
No information avaliable
EPA Patient Information
No information avaliable
EPA Organisms Affected
No information avaliable
