Dynabac
Dynabac Brand names, Dynabac Analogs
Dynabac Brand Names Mixture
- No information avaliable
Dynabac Chemical_Formula
C42H78N2O14
Dynabac RX_link
http://www.rxlist.com/cgi/generic2/dirthromycin.htm
Dynabac fda sheet
Dynabac msds (material safety sheet)
Dynabac Synthesis Reference
No information avaliable
Dynabac Molecular Weight
835.074 g/mol
Dynabac Melting Point
No information avaliable
Dynabac H2O Solubility
Poor
Dynabac State
Solid
Dynabac LogP
2.833
Dynabac Dosage Forms
Tablets (enteric coated, 250mg)
Dynabac Indication
For the treatment of the following mild-to-moderate infections caused by susceptible strains of microorganisms: acute bacterial exacerbations of chronic bronchitis, secondary bacterial infection of acute bronchitis, community-acquired pneumonia, pharyngitis/tonsilitis, and uncomplicated skin and skin structure infections.
Dynabac Pharmacology
Dirithromycin is a pro-drug which is converted non-enzymatically during intestinal absorption into the microbiologically active moiety erythromycylamine. Erythromycylamine exerts its activity by binding to the 50S ribosomal subunits of susceptible mircoorganisms resulting in inhibition of protein synthesis. Dirithromycin/erythromycylamine has been shown to be active against most strains of the following microorganisms both in vitro and in clinical infections: Staphylococcus aureus (methicillin-susceptible strains only), Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Legionella pneumophila, Moraxella catarrhalis, and Mycoplasma pneumoniae.
Dynabac Absorption
Oral dirithromycin is rapidly absorbed, with an absolute bioavailability of approximately 10%. Dietary fat has little or no effect on the bioavailability of dirithromycin.
Dynabac side effects and Toxicity
The toxic symptoms following an overdose of a macrolide antibiotic may include nausea, vomiting, epigastric distress, and diarrhea.
Dynabac Patient Information
Dynabac Organisms Affected
Enteric bacteria and other eubacteria
