Dostinex
Brand names,
Dostinex
Analogs
Dostinex
Brand Names Mixture
Dostinex
Chemical_Formula
C26H37N5O2
Dostinex
RX_link
http://www.rxlist.com/cgi/generic3/cabergoline.htm
Dostinex
fda sheet
Dostinex
msds (material safety sheet)
Dostinex
Synthesis Reference
No information avaliable
Dostinex
Molecular Weight
451.604 g/mol
Dostinex
Melting Point
102 - 104 oC
Dostinex
H2O Solubility
Insoluble
Dostinex
State
Solid
Dostinex
LogP
2.855
Dostinex
Dosage Forms
Tablets for oral administration (0.5 mg)
Dostinex
Indication
For the treatment of hyperprolactinemic disorders, either idiopathic or due to pituitary adenomas.
Dostinex
Pharmacology
Cabergoline is a dopamine receptor agonist and uncategorized drug which suppresses the production of prolactin in pituitary gland. It is an ergot-derivative. It has at times been used as an adjunct to SSRI antidepressants as there is some evidence that it counteracts certain side effects of those drugs such as reduced libido and anorgasmia. It also has been suggested online that it has a possible recreational use in reducing or eliminating the male refractory period.
Dostinex
Absorption
First-pass effect is seen, however the absolute bioavailability is unknown.
Dostinex
side effects and Toxicity
Overdosage might be expected to produce nasal congestion, syncope, or hallucinations.
Dostinex
Patient Information
Dostinex
Organisms Affected
Humans and other mammals