Digibind
Digibind Brand names, Digibind Analogs
Digibind Brand Names Mixture
- Malarone (Atovaquone + Proguanil Hydrochloride)
- Malarone Pediatric (Atovaquone + Proguanil Hydrochloride)
Digibind Chemical_Formula
C6394H9908N1698O2011S58
Digibind RX_link
http://www.rxlist.com/cgi/generic3/digoxinfab.htm
Digibind fda sheet
Digibind msds (material safety sheet)
Digibind Synthesis Reference
No information avaliable
Digibind Molecular Weight
144602.257
Digibind Melting Point
61 oC (FAB fragment)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Digibind H2O Solubility
No information avaliable
Digibind State
Liquid
Digibind LogP
-0.385
Digibind Dosage Forms
Solution (IV infusion and injection)
Digibind Indication
For the treatment of digitoxin overdose or digitalis glycoside toxicity
Digibind Pharmacology
Digibind binds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body. The Fab fragment-digoxin complex accumulates in the blood, from which it is excreted by the kidney. The net effect is to shift the equilibrium away from binding of digoxin to its receptors in the body, thereby reversing its effects.
Digibind Absorption
No information avaliable
Digibind side effects and Toxicity
No information avaliable
Digibind Patient Information
No information avaliable
Digibind Organisms Affected
Humans and other mammals
