DigiFab
DigiFab Brand names, DigiFab Analogs
DigiFab Brand Names Mixture
- No information avaliable
DigiFab Chemical_Formula
C2085H3223N553O672S16
DigiFab RX_link
http://www.rxlist.com/cgi/generic3/digoxinfab.htm
DigiFab fda sheet
DigiFab msds (material safety sheet)
DigiFab Synthesis Reference
No information avaliable
DigiFab Molecular Weight
47301.7
DigiFab Melting Point
61 oC (FAB fragment) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
DigiFab H2O Solubility
No information avaliable
DigiFab State
Liquid
DigiFab LogP
-0.343
DigiFab Dosage Forms
Powder for solution
DigiFab Indication
For treatment of digitoxin overdose or digitalis glycoside toxicity
DigiFab Pharmacology
DigiFab binds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body. The Fab fragment-digoxin complex accumulates in the blood, from which it is excreted by the kidney. The net effect is to shift the equilibrium away from binding of digoxin to its receptors in the body, thereby reversing its effects
DigiFab Absorption
No information avaliable
DigiFab side effects and Toxicity
No information avaliable
DigiFab Patient Information
No information avaliable
DigiFab Organisms Affected
Humans and other mammals
