Desloratadine

• Antihistamines
• ATC:R06AX27

• Aerius
• Alavert
• Clarinex
• Clarinex Reditabs
• Claritin
• Claritin Reditabs
• Descarboethoxyloratadine
• Descarboethoxyoratidine
• Desloratadine [Usan]
• Desloratidine
• Loratadine

• Clarinex-D 12 Hour Extended Release Tablets (desloratadine + pseudoephedrine)

C₁₉H₁₉ClN₂

http://www.rxlist.com/cgi/generic3/clarinex.htm

Desloratadine FDA

No information avaliable

310.82 g/mol

No information avaliable

No information avaliable

Solid

3.232

Syrup; Tablet

For the relief of symptoms of seasonal allergic rhinitis, pruritus, reduction in the number of hives in patients with chronic idiopathic urticaria.

Desloratadine is a long-lasting antihistamine. Desloratadine is a second-generation H₁-receptor antagonist which has a selective and peripheral H1-antagonist action. Histamine is a chemical that causes many of the signs that are part of allergic reactions, for example, swelling of tissues. Histamine is released from histamine-storing cells (mast cells) and attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cell to be "activated," releasing other chemicals which produce the effects that we associate with allergy. Desloratadine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation of cells by histamine. Unlike most other antihistamines, Desloratadine does not enter the brain from the blood and, therefore, does not cause drowsiness.

No information avaliable

No information avaliable

No information avaliable

Humans and other mammals