Desloratadine
Desloratadine Brand names, Desloratadine Analogs
Desloratadine Brand Names Mixture
- Clarinex-D 12 Hour Extended Release Tablets (desloratadine + pseudoephedrine)
Desloratadine Chemical_Formula
C19H19ClN2
Desloratadine RX_link
http://www.rxlist.com/cgi/generic3/clarinex.htm
Desloratadine fda sheet
Desloratadine msds (material safety sheet)
Desloratadine Synthesis Reference
No information avaliable
Desloratadine Molecular Weight
310.82 g/mol
Desloratadine Melting Point
No information avaliable
Desloratadine H2O Solubility
No information avaliable
Desloratadine State
Solid
Desloratadine LogP
3.232
Desloratadine Dosage Forms
Syrup; Tablet
Desloratadine Indication
For the relief of symptoms of seasonal allergic rhinitis, pruritus, reduction in the number of hives in patients with chronic idiopathic urticaria.
Desloratadine Pharmacology
Desloratadine is a long-lasting antihistamine. Desloratadine is a second-generation H1-receptor antagonist which has a selective and peripheral H1-antagonist action. Histamine is a chemical that causes many of the signs that are part of allergic reactions, for example, swelling of tissues. Histamine is released from histamine-storing cells (mast cells) and attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cell to be "activated," releasing other chemicals which produce the effects that we associate with allergy. Desloratadine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation of cells by histamine. Unlike most other antihistamines, Desloratadine does not enter the brain from the blood and, therefore, does not cause drowsiness.
Desloratadine Absorption
No information avaliable
Desloratadine side effects and Toxicity
No information avaliable
Desloratadine Patient Information
No information avaliable
Desloratadine Organisms Affected
Humans and other mammals
